Cargando…
Protection of Human Lens Epithelial Cells from Oxidative Stress Damage and Cell Apoptosis by KGF-2 through the Akt/Nrf2/HO-1 Pathway
Oxidative stress exerts a significant influence on the pathogenesis of various cataracts by inducing degradation and aggregation of lens proteins and apoptosis of lens epithelial cells. Keratinocyte growth factor−2 (KGF-2) exerts a favorable cytoprotective effect against oxidative stress in vivo and...
Autores principales: | Liu, Shuyu, Jin, Zi, Xia, Ruyue, Zheng, Zhuoni, Zha, Yi, Wang, Qiang, Wan, Xinbei, Yang, Hui, Cai, Jianqiu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8872674/ https://www.ncbi.nlm.nih.gov/pubmed/35222803 http://dx.doi.org/10.1155/2022/6933812 |
Ejemplares similares
-
FOXO1 Couples KGF and PI-3K/AKT Signaling to NKX2.1-Regulated Differentiation of Alveolar Epithelial Cells
por: Zhong, Qian, et al.
Publicado: (2022) -
Activation of Nrf2/HO-1 Antioxidant Pathway by Heme Attenuates Calcification of Human Lens Epithelial Cells
por: Chowdhury, Arpan, et al.
Publicado: (2022) -
Ferulic Acid Protects Human Lens Epithelial Cells against Ionizing Radiation-Induced Oxidative Damage by Activating Nrf2/HO-1 Signal Pathway
por: Chen, Yueqin, et al.
Publicado: (2022) -
AhR-E2F1-KGFR signaling is involved in KGF-induced intestinal epithelial cell proliferation
por: Yang, Kunqiu, et al.
Publicado: (2017) -
rhKGF-2 Attenuates Smoke Inhalation Lung Injury of Rats via Activating PI3K/Akt/Nrf2 and Repressing FoxO1-NLRP3 Inflammasome
por: Fu, Zhonghua, et al.
Publicado: (2021)