Beneficial effects of citrulline enteral administration on sepsis-induced T cell mitochondrial dysfunction

Severe sepsis induces a sustained immune dysfunction associated with poor clinical behavior. In particular, lymphopenia along with increased lymphocyte apoptosis and decreased lymphocyte proliferation, enhanced circulating regulatory T cells (Treg), and the emergence of myeloid-derived suppressor ce...

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Detalles Bibliográficos
Autores principales: Reizine, Florian, Grégoire, Murielle, Lesouhaitier, Mathieu, Coirier, Valentin, Gauthier, Juliette, Delaloy, Céline, Dessauge, Elise, Creusat, Florent, Uhel, Fabrice, Gacouin, Arnaud, Dessauge, Frédéric, Le Naoures, Cécile, Moreau, Caroline, Bendavid, Claude, Daniel, Yoann, Petitjean, Kilian, Bordeau, Valérie, Lamaison, Claire, Piau, Caroline, Cattoir, Vincent, Roussel, Mikael, Fromenty, Bernard, Michelet, Christian, Le Tulzo, Yves, Zmijewski, Jaroslaw, Thibault, Ronan, Cogné, Michel, Tarte, Karin, Tadié, Jean-Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8872724/
https://www.ncbi.nlm.nih.gov/pubmed/35173051
http://dx.doi.org/10.1073/pnas.2115139119

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