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Alkalosis-induced hypoventilation in cystic fibrosis: The importance of efficient renal adaptation

The lungs and kidneys are pivotal organs in the regulation of body acid–base homeostasis. In cystic fibrosis (CF), the impaired renal ability to excrete an excess amount of HCO(3)(−) into the urine leads to metabolic alkalosis [P. Berg et al., J. Am. Soc. Nephrol. 31, 1711–1727 (2020); F. Al-Ghimlas...

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Detalles Bibliográficos
Autores principales: Berg, Peder, Andersen, Jesper Frank, Sørensen, Mads Vaarby, Wang, Tobias, Malte, Hans, Leipziger, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8872776/
https://www.ncbi.nlm.nih.gov/pubmed/35173044
http://dx.doi.org/10.1073/pnas.2116836119

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