Molecular basis of force-pCa relation in MYL2 cardiomyopathy mice: Role of the super-relaxed state of myosin

In this study, we investigated the role of the super-relaxed (SRX) state of myosin in the structure–function relationship of sarcomeres in the hearts of mouse models of cardiomyopathy-bearing mutations in the human ventricular regulatory light chain (RLC, MYL2 gene). Skinned papillary muscles from h...

Descripción completa

Detalles Bibliográficos
Autores principales: Yuan, Chen-Ching, Kazmierczak, Katarzyna, Liang, Jingsheng, Ma, Weikang, Irving, Thomas C., Szczesna-Cordary, Danuta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8872785/
https://www.ncbi.nlm.nih.gov/pubmed/35177471
http://dx.doi.org/10.1073/pnas.2110328119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8872785/
https://www.ncbi.nlm.nih.gov/pubmed/35177471
http://dx.doi.org/10.1073/pnas.2110328119

Ejemplares similares