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Molecular basis of force-pCa relation in MYL2 cardiomyopathy mice: Role of the super-relaxed state of myosin

In this study, we investigated the role of the super-relaxed (SRX) state of myosin in the structure–function relationship of sarcomeres in the hearts of mouse models of cardiomyopathy-bearing mutations in the human ventricular regulatory light chain (RLC, MYL2 gene). Skinned papillary muscles from h...

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Detalles Bibliográficos
Autores principales:	Yuan, Chen-Ching, Kazmierczak, Katarzyna, Liang, Jingsheng, Ma, Weikang, Irving, Thomas C., Szczesna-Cordary, Danuta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2022
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8872785/ https://www.ncbi.nlm.nih.gov/pubmed/35177471 http://dx.doi.org/10.1073/pnas.2110328119

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