Strong influenza-induced T(FH) generation requires CD4 effectors to recognize antigen locally and receive signals from continuing infection

While influenza infection induces robust, long-lasting, antibody responses and protection, including the T follicular helper cells (T(FH)) required to drive B cell germinal center (GC) responses, most influenza vaccines do not. We investigated the mechanisms that drive strong T(FH) responses during...

Descripción completa

Detalles Bibliográficos
Autores principales: Devarajan, Priyadharshini, Vong, Allen M., Castonguay, Catherine H., Kugler-Umana, Olivia, Bautista, Bianca L., Jones, Michael C., Kelly, Karen A., Xia, Jingya, Swain, Susan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8872786/
https://www.ncbi.nlm.nih.gov/pubmed/35177472
http://dx.doi.org/10.1073/pnas.2111064119

Ejemplares similares

Ejemplares similares