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MadR mediates acyl CoA-dependent regulation of mycolic acid desaturation in mycobacteria

Mycobacterium tuberculosis has a lipid-rich cell envelope that is remodeled throughout infection to enable adaptation within the host. Few transcriptional regulators have been characterized that coordinate synthesis of mycolic acids, the major cell wall lipids of mycobacteria. Here, we show that the...

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Detalles Bibliográficos
Autores principales:	Cooper, Charlotte, Peterson, Eliza J. R., Bailo, Rebeca, Pan, Min, Singh, Albel, Moynihan, Patrick, Nakaya, Makoto, Fujiwara, Nagatoshi, Baliga, Nitin, Bhatt, Apoorva
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2022
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8872791/ https://www.ncbi.nlm.nih.gov/pubmed/35165190 http://dx.doi.org/10.1073/pnas.2111059119

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