The atypical Rho GTPase Rnd2 is critical for dentate granule neuron development and anxiety-like behavior during adult but not neonatal neurogenesis

Despite the central role of Rho GTPases in neuronal development, their functions in adult hippocampal neurogenesis remain poorly explored. Here, by using a retrovirus-based loss-of-function approach in vivo, we show that the atypical Rho GTPase Rnd2 is crucial for survival, positioning, somatodendri...

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Detalles Bibliográficos
Autores principales: Kerloch, Thomas, Farrugia, Fanny, Bouit, Lou, Maître, Marlène, Terral, Geoffrey, Koehl, Muriel, Mortessagne, Pierre, Heng, Julian Ik-Tsen, Blanchard, Mylène, Doat, Hélène, Leste-Lasserre, Thierry, Goron, Adeline, Gonzales, Delphine, Perrais, David, Guillemot, François, Abrous, Djoher Nora, Pacary, Emilie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8872985/
https://www.ncbi.nlm.nih.gov/pubmed/34561615
http://dx.doi.org/10.1038/s41380-021-01301-z

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