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2D Materials for Cardiac Tissue Repair and Regeneration

Cardiovascular diseases (CVDs) have a massive impact on human health. Due to the limited regeneration capacity of adult heart tissue, CVDs are the leading cause of death and disability worldwide. Even though there are surgical and pharmacological treatments for CVDs, regenerative strategies are the...

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Autores principales: Gokce, Cemile, Gurcan, Cansu, Delogu, Lucia Gemma, Yilmazer, Acelya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8873146/
https://www.ncbi.nlm.nih.gov/pubmed/35224044
http://dx.doi.org/10.3389/fcvm.2022.802551
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author Gokce, Cemile
Gurcan, Cansu
Delogu, Lucia Gemma
Yilmazer, Acelya
author_facet Gokce, Cemile
Gurcan, Cansu
Delogu, Lucia Gemma
Yilmazer, Acelya
author_sort Gokce, Cemile
collection PubMed
description Cardiovascular diseases (CVDs) have a massive impact on human health. Due to the limited regeneration capacity of adult heart tissue, CVDs are the leading cause of death and disability worldwide. Even though there are surgical and pharmacological treatments for CVDs, regenerative strategies are the most promising approaches and have the potential to benefit millions of people. As in any other tissue engineering approach, the repair and regeneration of damaged cardiac tissues generally involve scaffolds made up of biodegradable and biocompatible materials, cellular components such as stem cells, and growth factors. This review provides an overview of biomaterial-based tissue engineering approaches for CVDs with a specific focus on the potential of 2D materials. It is essential to consider both physicochemical and immunomodulatory properties for evaluating the applicability of 2D materials in cardiac tissue repair and regeneration. As new members of the 2D materials will be explored, they will quickly become part of cardiac tissue engineering technologies.
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spelling pubmed-88731462022-02-26 2D Materials for Cardiac Tissue Repair and Regeneration Gokce, Cemile Gurcan, Cansu Delogu, Lucia Gemma Yilmazer, Acelya Front Cardiovasc Med Cardiovascular Medicine Cardiovascular diseases (CVDs) have a massive impact on human health. Due to the limited regeneration capacity of adult heart tissue, CVDs are the leading cause of death and disability worldwide. Even though there are surgical and pharmacological treatments for CVDs, regenerative strategies are the most promising approaches and have the potential to benefit millions of people. As in any other tissue engineering approach, the repair and regeneration of damaged cardiac tissues generally involve scaffolds made up of biodegradable and biocompatible materials, cellular components such as stem cells, and growth factors. This review provides an overview of biomaterial-based tissue engineering approaches for CVDs with a specific focus on the potential of 2D materials. It is essential to consider both physicochemical and immunomodulatory properties for evaluating the applicability of 2D materials in cardiac tissue repair and regeneration. As new members of the 2D materials will be explored, they will quickly become part of cardiac tissue engineering technologies. Frontiers Media S.A. 2022-02-11 /pmc/articles/PMC8873146/ /pubmed/35224044 http://dx.doi.org/10.3389/fcvm.2022.802551 Text en Copyright © 2022 Gokce, Gurcan, Delogu and Yilmazer. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cardiovascular Medicine
Gokce, Cemile
Gurcan, Cansu
Delogu, Lucia Gemma
Yilmazer, Acelya
2D Materials for Cardiac Tissue Repair and Regeneration
title 2D Materials for Cardiac Tissue Repair and Regeneration
title_full 2D Materials for Cardiac Tissue Repair and Regeneration
title_fullStr 2D Materials for Cardiac Tissue Repair and Regeneration
title_full_unstemmed 2D Materials for Cardiac Tissue Repair and Regeneration
title_short 2D Materials for Cardiac Tissue Repair and Regeneration
title_sort 2d materials for cardiac tissue repair and regeneration
topic Cardiovascular Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8873146/
https://www.ncbi.nlm.nih.gov/pubmed/35224044
http://dx.doi.org/10.3389/fcvm.2022.802551
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