Inactivation of AUF1 in Myeloid Cells Protects From Allergic Airway and Tumor Infiltration and Impairs the Adenosine-Induced Polarization of Pro-Angiogenic Macrophages

The four isoforms of the RNA-binding protein hnRNPD/AUF1 have been proposed to limit the use of inflammatory mRNAs in innate immune cells. Mice engineered to lack AUF1s in all tissues are sensitive to acute inflammatory assaults; however, they also manifest complex degenerations obscuring assessment...

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Detalles Bibliográficos
Autores principales: Gargani, Sofia, Lourou, Niki, Arapatzi, Christina, Tzanos, Dimitris, Saridaki, Marania, Dushku, Esmeralda, Chatzimike, Margarita, Sidiropoulos, Nikolaos D., Andreadou, Margarita, Ntafis, Vasileios, Hatzis, Pantelis, Kostourou, Vassiliki, Kontoyiannis, Dimitris L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8873154/
https://www.ncbi.nlm.nih.gov/pubmed/35222366
http://dx.doi.org/10.3389/fimmu.2022.752215

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