Modelling Chlamydia and HPV co-infection in patient-derived ectocervix organoids reveals distinct cellular reprogramming

Coinfections with pathogenic microbes continually confront cervical mucosa, yet their implications in pathogenesis remain unclear. Lack of in-vitro models recapitulating cervical epithelium has been a bottleneck to study coinfections. Using patient-derived ectocervical organoids, we systematically m...

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Detalles Bibliográficos
Autores principales: Koster, Stefanie, Gurumurthy, Rajendra Kumar, Kumar, Naveen, Prakash, Pon Ganish, Dhanraj, Jayabhuvaneshwari, Bayer, Sofia, Berger, Hilmar, Kurian, Shilpa Mary, Drabkina, Marina, Mollenkopf, Hans-Joachim, Goosmann, Christian, Brinkmann, Volker, Nagel, Zachary, Mangler, Mandy, Meyer, Thomas F., Chumduri, Cindrilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8873204/
https://www.ncbi.nlm.nih.gov/pubmed/35210413
http://dx.doi.org/10.1038/s41467-022-28569-1

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