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Osteoblast-derived vesicles induce a switch from bone-formation to bone-resorption in vivo
Bone metabolism is regulated by the cooperative activity between bone-forming osteoblasts and bone-resorbing osteoclasts. However, the mechanisms mediating the switch between the osteoblastic and osteoclastic phases have not been fully elucidated. Here, we identify a specific subset of mature osteob...
Autores principales: | Uenaka, Maki, Yamashita, Erika, Kikuta, Junichi, Morimoto, Akito, Ao, Tomoka, Mizuno, Hiroki, Furuya, Masayuki, Hasegawa, Tetsuo, Tsukazaki, Hiroyuki, Sudo, Takao, Nishikawa, Keizo, Okuzaki, Daisuke, Motooka, Daisuke, Kosaka, Nobuyoshi, Sugihara, Fuminori, Boettger, Thomas, Braun, Thomas, Ochiya, Takahiro, Ishii, Masaru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8873258/ https://www.ncbi.nlm.nih.gov/pubmed/35210428 http://dx.doi.org/10.1038/s41467-022-28673-2 |
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