The mechanosensitive lncRNA Neat1 promotes osteoblast function through paraspeckle-dependent Smurf1 mRNA retention

Mechanical stimulation plays an important role in bone remodeling. Exercise-induced mechanical loading enhances bone strength, whereas mechanical unloading leads to bone loss. Increasing evidence has demonstrated that long noncoding RNAs (lncRNAs) play key roles in diverse biological, physiological...

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Detalles Bibliográficos
Autores principales: Liu, Caizhi, Gao, Xingcheng, Li, Yuheng, Sun, Weijia, Xu, Youjia, Tan, Yingjun, Du, Ruikai, Zhong, Guohui, Zhao, Dingsheng, Liu, Zizhong, Jin, Xiaoyan, Zhao, Yinlong, Wang, Yinbo, Yuan, Xinxin, Pan, Junjie, Yuan, Guodong, Li, Youyou, Xing, Wenjuan, Kan, Guanghan, Wang, Yanqing, Li, Qi, Han, Xuan, Li, Jianwei, Ling, Shukuan, Li, Yingxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8873336/
https://www.ncbi.nlm.nih.gov/pubmed/35210394
http://dx.doi.org/10.1038/s41413-022-00191-3

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