Aberrantly expressed Wnt5a in nurse-like cells drives resistance to Venetoclax in chronic lymphocytic leukemia

Chronic lymphocytic leukemia (CLL) is characterized by the accumulation of neoplastic B lymphocytes with high levels of Wnt5a in the plasma. Currently, the cell source of Wnt5a remains controversial. The receptor of Wnt5a is ROR1, whose expression is associated with disease progression and resistanc...

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Detalles Bibliográficos
Autores principales: Guo, Yao, Pei, Hanzhong, Lu, Bo, Zhang, Dengyang, Zhao, Yuming, Wu, Fuqun, Sun, Honghua, Huang, Junbin, Li, Peng, Yi, Chenju, Zhu, Chengming, Pan, Yihang, Wu, Shunjie, Chen, Chun, Xu, Xiaojun, Chen, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8873424/
https://www.ncbi.nlm.nih.gov/pubmed/35210425
http://dx.doi.org/10.1038/s41420-022-00884-y

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