Cargando…

METTL3 suppresses neuropathic pain via modulating N6-methyladenosine-dependent primary miR-150 processing

Methyltransferase-like 3 (METTL3)-modulated N6-methyladenosine (m6A) was recently identified as an important epigenetic regulation type during RNA processing and contributes to multiple pathological processes. Neuropathic pain (NP) is induced by a lesion of the somatosensory nervous system, and the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Le, Zhao, Xin, Wang, Jing, Jin, Yanwu, Gong, Moxuan, Ye, Yuyang, Li, Peilong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8873433/ https://www.ncbi.nlm.nih.gov/pubmed/35210391 http://dx.doi.org/10.1038/s41420-022-00880-2

Ejemplares similares

METTL14 Suppresses CRC Progression via Regulating N6-Methyladenosine-Dependent Primary miR-375 Processing
por: Chen, Xiaoxiang, et al.
Publicado: (2020)

Retraction Notice to: METTL14 Suppresses CRC Progression via Regulating N6-Methyladenosine-Dependent Primary miR-375 Processing
por: Chen, Xiaoxiang, et al.
Publicado: (2022)

Solution structure of the RNA recognition domain of METTL3-METTL14 N(6)-methyladenosine methyltransferase
por: Huang, Jinbo, et al.
Publicado: (2018)

METTL3 Induces AAA Development and Progression by Modulating N6-Methyladenosine-Dependent Primary miR34a Processing
por: Zhong, Lintao, et al.
Publicado: (2020)

N (6)-methyladenosine modification and METTL3 modulate enterovirus 71 replication
por: Hao, Haojie, et al.
Publicado: (2019)

Exploration of N6-Methyladenosine Profiles of mRNAs and the Function of METTL3 in Atherosclerosis
por: Zhou, Yaqing, et al.
Publicado: (2022)

METTL14 promotes the migration and invasion of breast cancer cells by modulating N6-methyladenosine and hsa-miR-146a-5p expression
por: Yi, Dandan, et al.
Publicado: (2020)

Long Non-coding RNA LINC01119 Promotes Neuropathic Pain by Stabilizing BDNF Transcript
por: Zhang, Le, et al.
Publicado: (2021)

Suppression of Wnt/β-catenin Signaling in PDAC via METTL16-mediated N6-methyladenosine Modification of DVL2
por: Yu, Lanting, et al.
Publicado: (2023)

Non-coding RNA and n6-methyladenosine modification play crucial roles in neuropathic pain
por: Zhang, Kexin, et al.
Publicado: (2022)

The N(6)-Methyladenosine mRNA Methylase METTL3 Controls Cardiac Homeostasis and Hypertrophy
por: Dorn, Lisa E., et al.
Publicado: (2019)

Multifaceted Roles of the N(6)-Methyladenosine RNA Methyltransferase METTL3 in Cancer and Immune Microenvironment
por: Hu, Chenxi, et al.
Publicado: (2022)

The N(6)-methyladenosine methyltransferase METTL16 enables erythropoiesis through safeguarding genome integrity
por: Yoshinaga, Masanori, et al.
Publicado: (2022)

The RNA N6-Methyladenosine Methyltransferase METTL3 Promotes the Progression of Kidney Cancer via N6-Methyladenosine-Dependent Translational Enhancement of ABCD1
por: Shi, Yue, et al.
Publicado: (2021)

Downregulation of N(6)-methyladenosine binding YTHDF2 protein mediated by miR-493-3p suppresses prostate cancer by elevating N(6)-methyladenosine levels
por: Li, Jiangfeng, et al.
Publicado: (2017)

MicroRNA-150 (miR-150) and Diabetic Retinopathy: Is miR-150 Only a Biomarker or Does It Contribute to Disease Progression?
por: Ko, Gladys Y.-P., et al.
Publicado: (2022)

N(6)-Methyladenosine METTL3 Modulates the Proliferation and Apoptosis of Lens Epithelial Cells in Diabetic Cataract
por: Yang, Jun, et al.
Publicado: (2020)

METTL3-mediated mRNA N(6)-methyladenosine is required for oocyte and follicle development in mice
por: Mu, Haiyuan, et al.
Publicado: (2021)

N-6-Methyladenosine in Vasoactive microRNAs during Hypoxia; A Novel Role for METTL4
por: van den Homberg, Daphne A. L., et al.
Publicado: (2022)

METTL3-Dependent N6-Methyladenosine Modification Programs Human Neural Progenitor Cell Proliferation
por: Zhao, Yuan, et al.
Publicado: (2023)

METTL14 is a chromatin regulator independent of its RNA N(6)-methyladenosine methyltransferase activity
por: Dou, Xiaoyang, et al.
Publicado: (2023)

miR-150 Suppresses Tumor Growth in Melanoma Through Downregulation of MYB
por: Sun, Xiyan, et al.
Publicado: (2019)

Adipose METTL14‐Elicited N(6)‐Methyladenosine Promotes Obesity, Insulin Resistance, and NAFLD Through Suppressing β Adrenergic Signaling and Lipolysis
por: Kang, Qianqian, et al.
Publicado: (2023)

METTL3-mediated N(6)-methyladenosine mRNA modification enhances long-term memory consolidation
por: Zhang, Zeyu, et al.
Publicado: (2018)

METTL3-mediated N6-methyladenosine modification is critical for epithelial-mesenchymal transition and metastasis of gastric cancer
por: Yue, Ben, et al.
Publicado: (2019)

METTL3-Mediated N6-Methyladenosine Modification Is Involved in the Dysregulation of NRIP1 Expression in Down Syndrome
por: Shi, Weili, et al.
Publicado: (2021)

Prognostic Roles of N6-Methyladenosine METTL3 in Different Cancers: A System Review and Meta-Analysis
por: Liu, KuangZheng, et al.
Publicado: (2021)

Acute depletion of METTL3 implicates N(6)-methyladenosine in alternative intron/exon inclusion in the nascent transcriptome
por: Wei, Guifeng, et al.
Publicado: (2021)

N6-Methyladenosine Methyltransferase METTL14-Mediated Autophagy in Malignant Development of Oral Squamous Cell Carcinoma
por: Wang, Fang, et al.
Publicado: (2021)

TCF4 and HuR mediated-METTL14 suppresses dissemination of colorectal cancer via N6-methyladenosine-dependent silencing of ARRDC4
por: Wang, Hao, et al.
Publicado: (2021)

miR-150: targeting MLL leukemia
por: Jiang, Xi, et al.
Publicado: (2012)

METTL3 Is Suppressed by Circular RNA circMETTL3/miR-34c-3p Signaling and Limits the Tumor Growth and Metastasis in Triple Negative Breast Cancer
por: Ruan, Han-guang, et al.
Publicado: (2021)

Analysis of N6-Methyladenosine Methyltransferase Reveals METTL14 and ZC3H13 as Tumor Suppressor Genes in Breast Cancer
por: Gong, Peng-Ju, et al.
Publicado: (2020)

METTL3/N6‐methyladenosine/ miR‐21‐5p promotes obstructive renal fibrosis by regulating inflammation through SPRY1/ERK/NF‐κB pathway activation
por: Liu, Erpeng, et al.
Publicado: (2021)

Mettl14 inhibits bladder TIC self-renewal and bladder tumorigenesis through N(6)-methyladenosine of Notch1
por: Gu, Chaohui, et al.
Publicado: (2019)

METTL14 aggravates podocyte injury and glomerulopathy progression through N(6)-methyladenosine-dependent downregulating of Sirt1
por: Lu, Zhihui, et al.
Publicado: (2021)

miR-150 inhibits terminal erythroid proliferation and differentiation
por: Sun, Zhiwei, et al.
Publicado: (2015)

MiR-150-3p targets SP1 and suppresses the growth of glioma cells
por: Tan, Zhigang, et al.
Publicado: (2018)

miR-150-5p suppresses tumor progression by targeting VEGFA in colorectal cancer
por: Chen, Xiaoxiang, et al.
Publicado: (2018)

N(6)‐Methyladenosine Demethylase FTO Contributes to Neuropathic Pain by Stabilizing G9a Expression in Primary Sensory Neurons
por: Li, Yize, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_o4qhbq1ipl8vqlvao8anuc0557