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Proposing a novel deep network for detecting COVID-19 based on chest images

The rapid outbreak of coronavirus threatens humans’ life all around the world. Due to the insufficient diagnostic infrastructures, developing an accurate, efficient, inexpensive, and quick diagnostic tool is of great importance. To date, researchers have proposed several detection models based on ch...

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Autores principales: Dialameh, Maryam, Hamzeh, Ali, Rahmani, Hossein, Radmard, Amir Reza, Dialameh, Safoura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8873454/
https://www.ncbi.nlm.nih.gov/pubmed/35210447
http://dx.doi.org/10.1038/s41598-022-06802-7
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author Dialameh, Maryam
Hamzeh, Ali
Rahmani, Hossein
Radmard, Amir Reza
Dialameh, Safoura
author_facet Dialameh, Maryam
Hamzeh, Ali
Rahmani, Hossein
Radmard, Amir Reza
Dialameh, Safoura
author_sort Dialameh, Maryam
collection PubMed
description The rapid outbreak of coronavirus threatens humans’ life all around the world. Due to the insufficient diagnostic infrastructures, developing an accurate, efficient, inexpensive, and quick diagnostic tool is of great importance. To date, researchers have proposed several detection models based on chest imaging analysis, primarily based on deep neural networks; however, none of which could achieve a reliable and highly sensitive performance yet. Therefore, the nature of this study is primary epidemiological research that aims to overcome the limitations mentioned above by proposing a large-scale publicly available dataset of chest computed tomography scan (CT-scan) images consisting of more than 13k samples. Secondly, we propose a more sensitive deep neural networks model for CT-scan images of the lungs, providing a pixel-wise attention layer on top of the high-level features extracted from the network. Moreover, the proposed model is extended through a transfer learning approach for being applicable in the case of chest X-Ray (CXR) images. The proposed model and its extension have been trained and evaluated through several experiments. The inclusion criteria were patients with suspected PE and positive real-time reverse-transcription polymerase chain reaction (RT-PCR) for SARS-CoV-2. The exclusion criteria were negative or inconclusive RT-PCR and other chest CT indications. Our model achieves an AUC score of 0.886, significantly better than its closest competitor, whose AUC is 0.843. Moreover, the obtained results on another commonly-used benchmark show an AUC of 0.899, outperforming related models. Additionally, the sensitivity of our model is 0.858, while that of its closest competitor is 0.81, explaining the efficiency of pixel-wise attention strategy in detecting coronavirus. Our promising results and the efficiency of the models imply that the proposed models can be considered reliable tools for assisting doctors in detecting coronavirus.
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spelling pubmed-88734542022-02-25 Proposing a novel deep network for detecting COVID-19 based on chest images Dialameh, Maryam Hamzeh, Ali Rahmani, Hossein Radmard, Amir Reza Dialameh, Safoura Sci Rep Article The rapid outbreak of coronavirus threatens humans’ life all around the world. Due to the insufficient diagnostic infrastructures, developing an accurate, efficient, inexpensive, and quick diagnostic tool is of great importance. To date, researchers have proposed several detection models based on chest imaging analysis, primarily based on deep neural networks; however, none of which could achieve a reliable and highly sensitive performance yet. Therefore, the nature of this study is primary epidemiological research that aims to overcome the limitations mentioned above by proposing a large-scale publicly available dataset of chest computed tomography scan (CT-scan) images consisting of more than 13k samples. Secondly, we propose a more sensitive deep neural networks model for CT-scan images of the lungs, providing a pixel-wise attention layer on top of the high-level features extracted from the network. Moreover, the proposed model is extended through a transfer learning approach for being applicable in the case of chest X-Ray (CXR) images. The proposed model and its extension have been trained and evaluated through several experiments. The inclusion criteria were patients with suspected PE and positive real-time reverse-transcription polymerase chain reaction (RT-PCR) for SARS-CoV-2. The exclusion criteria were negative or inconclusive RT-PCR and other chest CT indications. Our model achieves an AUC score of 0.886, significantly better than its closest competitor, whose AUC is 0.843. Moreover, the obtained results on another commonly-used benchmark show an AUC of 0.899, outperforming related models. Additionally, the sensitivity of our model is 0.858, while that of its closest competitor is 0.81, explaining the efficiency of pixel-wise attention strategy in detecting coronavirus. Our promising results and the efficiency of the models imply that the proposed models can be considered reliable tools for assisting doctors in detecting coronavirus. Nature Publishing Group UK 2022-02-24 /pmc/articles/PMC8873454/ /pubmed/35210447 http://dx.doi.org/10.1038/s41598-022-06802-7 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Dialameh, Maryam
Hamzeh, Ali
Rahmani, Hossein
Radmard, Amir Reza
Dialameh, Safoura
Proposing a novel deep network for detecting COVID-19 based on chest images
title Proposing a novel deep network for detecting COVID-19 based on chest images
title_full Proposing a novel deep network for detecting COVID-19 based on chest images
title_fullStr Proposing a novel deep network for detecting COVID-19 based on chest images
title_full_unstemmed Proposing a novel deep network for detecting COVID-19 based on chest images
title_short Proposing a novel deep network for detecting COVID-19 based on chest images
title_sort proposing a novel deep network for detecting covid-19 based on chest images
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8873454/
https://www.ncbi.nlm.nih.gov/pubmed/35210447
http://dx.doi.org/10.1038/s41598-022-06802-7
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