Multi-omic characterization of genome-wide abnormal DNA methylation reveals diagnostic and prognostic markers for esophageal squamous-cell carcinoma

This study investigates aberrant DNA methylations as potential diagnosis and prognosis markers for esophageal squamous-cell carcinoma (ESCC), which if diagnosed at advanced stages has <30% five-year survival rate. Comparing genome-wide methylation sites of 91 ESCC and matched adjacent normal tiss...

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Detalles Bibliográficos
Autores principales: Xi, Yiyi, Lin, Yuan, Guo, Wenjia, Wang, Xinyu, Zhao, Hengqiang, Miao, Chuanwang, Liu, Weiling, Liu, Yachen, Liu, Tianyuan, Luo, Yingying, Fan, Wenyi, Lin, Ai, Chen, Yamei, Sun, Yanxia, Ma, Yulin, Niu, Xiangjie, Zhong, Ce, Tan, Wen, Zhou, Meng, Su, Jianzhong, Wu, Chen, Lin, Dongxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8873499/
https://www.ncbi.nlm.nih.gov/pubmed/35210398
http://dx.doi.org/10.1038/s41392-022-00873-8

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