Exosomes Mediate APP Dysregulation via APP-miR-185-5p Axis

APP misexpression plays a crucial role in triggering a complex pathological cascade, leading to Alzheimer’s disease (AD). But how the expression of APP is regulated in pathological conditions remains poorly understood. In this study, we found that the exosomes isolated from AD mouse brain promoted A...

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Detalles Bibliográficos
Autores principales: Ding, Lu, Yang, Xiaoyu, Xia, Xiaohuan, Li, Yunxia, Wang, Yi, Li, Chunhong, Sun, Yiyan, Gao, Ge, Zhao, Shu, Sheng, Shiyang, Liu, Jianhui, Zheng, Jialin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8873530/
https://www.ncbi.nlm.nih.gov/pubmed/35223832
http://dx.doi.org/10.3389/fcell.2022.793388

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