Identification of novel STAT5B mutations and characterization of TCRβ signatures in CD4+ T-cell large granular lymphocyte leukemia

CD4+ T-cell large granular lymphocyte leukemia (T-LGLL) is a rare subtype of T-LGLL with unknown etiology. In this study, we molecularly characterized a cohort of patients (n = 35) by studying their T-cell receptor (TCR) repertoire and the presence of somatic STAT5B mutations. In addition to the pre...

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Detalles Bibliográficos
Autores principales: Bhattacharya, Dipabarna, Teramo, Antonella, Gasparini, Vanessa Rebecca, Huuhtanen, Jani, Kim, Daehong, Theodoropoulos, Jason, Schiavoni, Gianluca, Barilà, Gregorio, Vicenzetto, Cristina, Calabretto, Giulia, Facco, Monica, Kawakami, Toru, Nakazawa, Hideyuki, Falini, Brunangelo, Tiacci, Enrico, Ishida, Fumihiro, Semenzato, Gianpietro, Kelkka, Tiina, Zambello, Renato, Mustjoki, Satu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8873566/
https://www.ncbi.nlm.nih.gov/pubmed/35210405
http://dx.doi.org/10.1038/s41408-022-00630-8

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