The Lifted Veil of Uncommon EGFR Mutation p.L747P in Non-Small Cell Lung Cancer: Molecular Feature and Targeting Sensitivity to Tyrosine Kinase Inhibitors

OBJECTIVES: The uncommon p.L747P mutation in epidermal growth factor receptor (EGFR) exon 19 reveals to alter the response to tyrosine kinase inhibitors (TKIs) in patients diagnosed with advanced non-small cell lung cancer (NSCLC). However, the underlying mechanism is still not clear. This study aim...

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Detalles Bibliográficos
Autores principales: Yang, Guangjian, Liu, Chengming, Hu, Jiaqi, Sun, Yang, Hu, Peizeng, Liu, Liu, Xu, Haiyan, Li, Dazhou, Li, Weihua, Yang, Yaning, Sun, Nan, He, Jie, Wang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8873585/
https://www.ncbi.nlm.nih.gov/pubmed/35223527
http://dx.doi.org/10.3389/fonc.2022.843299

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