Pharmacologic Antagonization of Cannabinoid Receptor 1 Improves Cholestasis in Abcb4(-/-) Mice

BACKGROUND & AIMS: The endocannabinoid system is involved in the modulation of inflammatory, fibrotic, metabolic, and carcinogenesis-associated signaling pathways via cannabinoid receptor (CB)1 and CB2. We hypothesized that the pharmacologic antagonization of CB1 receptor improves cholestasis in...

Descripción completa

Detalles Bibliográficos
Autores principales: Helmrich, Nora, Roderfeld, Martin, Baier, Anne, Windhorst, Anita, Herebian, Diran, Mayatepek, Ertan, Dierkes, Christian, Ocker, Matthias, Glebe, Dieter, Christ, Bruno, Churin, Yuri, Irungbam, Karuna, Roeb, Elke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8873597/
https://www.ncbi.nlm.nih.gov/pubmed/34954190
http://dx.doi.org/10.1016/j.jcmgh.2021.12.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8873597/
https://www.ncbi.nlm.nih.gov/pubmed/34954190
http://dx.doi.org/10.1016/j.jcmgh.2021.12.013

Ejemplares similares