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Pharmacologic Antagonization of Cannabinoid Receptor 1 Improves Cholestasis in Abcb4(-/-) Mice

BACKGROUND & AIMS: The endocannabinoid system is involved in the modulation of inflammatory, fibrotic, metabolic, and carcinogenesis-associated signaling pathways via cannabinoid receptor (CB)1 and CB2. We hypothesized that the pharmacologic antagonization of CB1 receptor improves cholestasis in...

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Detalles Bibliográficos
Autores principales:	Helmrich, Nora, Roderfeld, Martin, Baier, Anne, Windhorst, Anita, Herebian, Diran, Mayatepek, Ertan, Dierkes, Christian, Ocker, Matthias, Glebe, Dieter, Christ, Bruno, Churin, Yuri, Irungbam, Karuna, Roeb, Elke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8873597/ https://www.ncbi.nlm.nih.gov/pubmed/34954190 http://dx.doi.org/10.1016/j.jcmgh.2021.12.013

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