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Tertiary lymphoid structure and decreased CD8(+) T cell infiltration in minimally invasive adenocarcinoma

Knowledge of the tumor microenvironment (TME) in patients with early lung cancer, especially in comparison with the matched adjacent tissues, remains lacking. To characterize TME of early-stage lung adenocarcinoma, we performed RNA-seq profiling on 58 pairs of minimally invasive adenocarcinoma (MIA)...

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Detalles Bibliográficos
Autores principales:	Wang, Jin, Jiang, Dongbo, Zheng, Xiaoqi, Li, Wang, Zhao, Tian, Wang, Di, Yu, Huansha, Sun, Dongqing, Li, Ziyi, Zhang, Jian, Zhang, Zhe, Hou, Likun, Jiang, Gening, Fei, Ke, Zhang, Fan, Yang, Kun, Zhang, Peng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8873609/ https://www.ncbi.nlm.nih.gov/pubmed/35243243 http://dx.doi.org/10.1016/j.isci.2022.103883

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