A Novel Mouse Model Harboring Hepatitis B Virus Covalently Closed Circular DNA

BACKGROUND AND AIMS: The persistence of viral covalently closed circular DNA (cccDNA) is the major obstacle for antiviral treatment against hepatitis B virus (HBV). Basic and translational studies are largely hampered due to the lack of feasible small animal models to support HBV cccDNA formation. T...

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Detalles Bibliográficos
Autores principales: Xu, Zaichao, Zhao, Li, Zhong, Youquan, Zhu, Chengliang, Zhao, Kaitao, Teng, Yan, Cheng, Xiaoming, Chen, Qiang, Xia, Yuchen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8873614/
https://www.ncbi.nlm.nih.gov/pubmed/34896285
http://dx.doi.org/10.1016/j.jcmgh.2021.11.011

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