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A High-Fat Diet Activates the BAs-FXR Axis and Triggers Cancer-Associated Fibroblast Properties in the Colon

BACKGROUND & AIMS: Dietary signals are known to modulate stemness and tumorigenicity of intestinal progenitors; however, the impact of a high-fat diet (HFD) on the intestinal stem cell (ISC) niche and its association with colorectal cancer remains unclear. Thus, we aimed to investigate how a HFD...

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Detalles Bibliográficos
Autores principales:	Kim, Tae-Young, Kim, Seungil, Kim, Yeji, Lee, Yong-Soo, Lee, Sohyeon, Lee, Su-Hyun, Kweon, Mi-Na
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8873938/ https://www.ncbi.nlm.nih.gov/pubmed/34971821 http://dx.doi.org/10.1016/j.jcmgh.2021.12.015

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