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Severe pneumonia: Treatment outcome and its determinant factors among under-five patients, Jimma, Ethiopia

INTRODUCTION: Over 2 million children die from pneumonia each year accounting for almost one in five children’s deaths worldwide which is estimated to be 18% of mortality cases. Therefore, this study is aimed to assess treatment outcome and its determinant factors among under-five patients, Jimma, E...

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Autores principales: Tegenu, Kenenisa, Geleto, Gelane, Tilahun, Desalew, Bayana, Ebissa, Bereke, Bayisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8873968/
https://www.ncbi.nlm.nih.gov/pubmed/35223030
http://dx.doi.org/10.1177/20503121221078445
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author Tegenu, Kenenisa
Geleto, Gelane
Tilahun, Desalew
Bayana, Ebissa
Bereke, Bayisa
author_facet Tegenu, Kenenisa
Geleto, Gelane
Tilahun, Desalew
Bayana, Ebissa
Bereke, Bayisa
author_sort Tegenu, Kenenisa
collection PubMed
description INTRODUCTION: Over 2 million children die from pneumonia each year accounting for almost one in five children’s deaths worldwide which is estimated to be 18% of mortality cases. Therefore, this study is aimed to assess treatment outcome and its determinant factors among under-five patients, Jimma, Ethiopia. METHODS: Study design was conducted on 522 under-five children with severe pneumonia from 1 January 2017 to 30 December 2020. Pretested chart review format was used to collect data. Data were entered into EpiData, version 3.1, and exported to Statistical Package for the Social Sciences, version 23, for analysis. Logistic regression analysis with 95% confidence interval was used to declare statistical significance at p value <0.05. RESULTS: Among 522 under-five children with severe pneumonia, majority (83.91%) of them were improved, whereas 1 over 6 (16.09%) of them were died. This finding showed that children who have malnutrition (adjusted odds ratio = 7.23 (3.17–14.51), p = 0.000), positive serostatus for HIV (adjusted odds ratio = 5.01 (1.91–12.13), p = 0.001), history of upper respiratory tract infections (adjusted odds ratio = 3.27 (1.55–6.91), p = 0.002), unvaccinated (adjusted odds ratio = 4.35 (1.60–11.79), p = 0.004), having complicated types of pneumonia (adjusted odds ratio = 8.48 (4.22–16.65), p < 0.001), and comorbidity disease (adjusted odds ratio = 5.21 (2.03–13.3), p < 0.001) were statistically significant with mortality. CONCLUSION: This study showed that mortality secondary to severe pneumonia was high. Being malnourished, positive serostatus for HIV infection, history of upper respiratory tract infections, unvaccinated, having complicated type of pneumonia, and other comorbidity disease were identified as determinant factors of mortality. Committed, harmonized, and integrated intervention needs to be taken to reduce mortality from severe pneumonia by enhancing child’s nutrition status, early detection and treatment, effectively vaccinating children, and preventing other comorbidity diseases.
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spelling pubmed-88739682022-02-26 Severe pneumonia: Treatment outcome and its determinant factors among under-five patients, Jimma, Ethiopia Tegenu, Kenenisa Geleto, Gelane Tilahun, Desalew Bayana, Ebissa Bereke, Bayisa SAGE Open Med Original Research Article INTRODUCTION: Over 2 million children die from pneumonia each year accounting for almost one in five children’s deaths worldwide which is estimated to be 18% of mortality cases. Therefore, this study is aimed to assess treatment outcome and its determinant factors among under-five patients, Jimma, Ethiopia. METHODS: Study design was conducted on 522 under-five children with severe pneumonia from 1 January 2017 to 30 December 2020. Pretested chart review format was used to collect data. Data were entered into EpiData, version 3.1, and exported to Statistical Package for the Social Sciences, version 23, for analysis. Logistic regression analysis with 95% confidence interval was used to declare statistical significance at p value <0.05. RESULTS: Among 522 under-five children with severe pneumonia, majority (83.91%) of them were improved, whereas 1 over 6 (16.09%) of them were died. This finding showed that children who have malnutrition (adjusted odds ratio = 7.23 (3.17–14.51), p = 0.000), positive serostatus for HIV (adjusted odds ratio = 5.01 (1.91–12.13), p = 0.001), history of upper respiratory tract infections (adjusted odds ratio = 3.27 (1.55–6.91), p = 0.002), unvaccinated (adjusted odds ratio = 4.35 (1.60–11.79), p = 0.004), having complicated types of pneumonia (adjusted odds ratio = 8.48 (4.22–16.65), p < 0.001), and comorbidity disease (adjusted odds ratio = 5.21 (2.03–13.3), p < 0.001) were statistically significant with mortality. CONCLUSION: This study showed that mortality secondary to severe pneumonia was high. Being malnourished, positive serostatus for HIV infection, history of upper respiratory tract infections, unvaccinated, having complicated type of pneumonia, and other comorbidity disease were identified as determinant factors of mortality. Committed, harmonized, and integrated intervention needs to be taken to reduce mortality from severe pneumonia by enhancing child’s nutrition status, early detection and treatment, effectively vaccinating children, and preventing other comorbidity diseases. SAGE Publications 2022-02-21 /pmc/articles/PMC8873968/ /pubmed/35223030 http://dx.doi.org/10.1177/20503121221078445 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Research Article
Tegenu, Kenenisa
Geleto, Gelane
Tilahun, Desalew
Bayana, Ebissa
Bereke, Bayisa
Severe pneumonia: Treatment outcome and its determinant factors among under-five patients, Jimma, Ethiopia
title Severe pneumonia: Treatment outcome and its determinant factors among under-five patients, Jimma, Ethiopia
title_full Severe pneumonia: Treatment outcome and its determinant factors among under-five patients, Jimma, Ethiopia
title_fullStr Severe pneumonia: Treatment outcome and its determinant factors among under-five patients, Jimma, Ethiopia
title_full_unstemmed Severe pneumonia: Treatment outcome and its determinant factors among under-five patients, Jimma, Ethiopia
title_short Severe pneumonia: Treatment outcome and its determinant factors among under-five patients, Jimma, Ethiopia
title_sort severe pneumonia: treatment outcome and its determinant factors among under-five patients, jimma, ethiopia
topic Original Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8873968/
https://www.ncbi.nlm.nih.gov/pubmed/35223030
http://dx.doi.org/10.1177/20503121221078445
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