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Detection of cytogenetic changes and chromosomal aneuploidy with fluorescent in situ hybridization in cytological specimens of oral cancers in Fanconi anemia—Proof of concept

OBJECTIVES: Fanconi anemia (FA) is a rare inherited DNA instability disorder with a remarkably elevated risk of neoplasia compared with the general population, mainly leukemia and squamous cell carcinoma (SCC). Two thirds of the SCCs arise in the oral cavity and are typically preceded by visible les...

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Detalles Bibliográficos
Autores principales: Silva de Araujo, Bruno Eduardo, Velleuer, Eunike, Dietrich, Ralf, Pomjanski, Natalia, de Santana Almeida Araujo, Isabela Karoline, Schlensog, Martin, Wells, Susanne Irmtraud, Dorsman, Josephine Christine, Schramm, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8874072/
https://www.ncbi.nlm.nih.gov/pubmed/34854575
http://dx.doi.org/10.1002/cre2.519