Long non‐coding RNAs in diabetic wound healing: Current research and clinical relevance

Diabetic wounds are a protracted complication of diabetes mainly characterised by chronic inflammation, obstruction of epithelialization, damaged blood vessels and collagen production (maturation), as well as neuropathy. As a non‐coding RNA (ncRNA) that lack coding potential, long non‐coding RNAs (l...

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Detalles Bibliográficos
Autores principales: Kuai, Le, Jiang, Jing‐Si, Li, Wei, Li, Bin, Yin, Shuang‐Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8874090/
https://www.ncbi.nlm.nih.gov/pubmed/34337861
http://dx.doi.org/10.1111/iwj.13655
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author Kuai, Le
Jiang, Jing‐Si
Li, Wei
Li, Bin
Yin, Shuang‐Yi
author_facet Kuai, Le
Jiang, Jing‐Si
Li, Wei
Li, Bin
Yin, Shuang‐Yi
author_sort Kuai, Le
collection PubMed
description Diabetic wounds are a protracted complication of diabetes mainly characterised by chronic inflammation, obstruction of epithelialization, damaged blood vessels and collagen production (maturation), as well as neuropathy. As a non‐coding RNA (ncRNA) that lack coding potential, long non‐coding RNAs (lncRNAs) have recently been reported to play a salient role in diabetic wound healing. Here, this review summarises the roles of lncRNAs in the pathology and treatments of diabetic wounds, providing references for its potential clinical diagnostic criteria or therapeutic targets in the future.
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spelling pubmed-88740902022-02-28 Long non‐coding RNAs in diabetic wound healing: Current research and clinical relevance Kuai, Le Jiang, Jing‐Si Li, Wei Li, Bin Yin, Shuang‐Yi Int Wound J Original Articles Diabetic wounds are a protracted complication of diabetes mainly characterised by chronic inflammation, obstruction of epithelialization, damaged blood vessels and collagen production (maturation), as well as neuropathy. As a non‐coding RNA (ncRNA) that lack coding potential, long non‐coding RNAs (lncRNAs) have recently been reported to play a salient role in diabetic wound healing. Here, this review summarises the roles of lncRNAs in the pathology and treatments of diabetic wounds, providing references for its potential clinical diagnostic criteria or therapeutic targets in the future. Blackwell Publishing Ltd 2021-08-02 /pmc/articles/PMC8874090/ /pubmed/34337861 http://dx.doi.org/10.1111/iwj.13655 Text en © 2021 The Authors. International Wound Journal published by Medicalhelplines.com Inc (3M) and John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Articles
Kuai, Le
Jiang, Jing‐Si
Li, Wei
Li, Bin
Yin, Shuang‐Yi
Long non‐coding RNAs in diabetic wound healing: Current research and clinical relevance
title Long non‐coding RNAs in diabetic wound healing: Current research and clinical relevance
title_full Long non‐coding RNAs in diabetic wound healing: Current research and clinical relevance
title_fullStr Long non‐coding RNAs in diabetic wound healing: Current research and clinical relevance
title_full_unstemmed Long non‐coding RNAs in diabetic wound healing: Current research and clinical relevance
title_short Long non‐coding RNAs in diabetic wound healing: Current research and clinical relevance
title_sort long non‐coding rnas in diabetic wound healing: current research and clinical relevance
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8874090/
https://www.ncbi.nlm.nih.gov/pubmed/34337861
http://dx.doi.org/10.1111/iwj.13655
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AT libin longnoncodingrnasindiabeticwoundhealingcurrentresearchandclinicalrelevance
AT yinshuangyi longnoncodingrnasindiabeticwoundhealingcurrentresearchandclinicalrelevance

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