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TRPV4 and PIEZO Channels Mediate the Mechanosensing of Chondrocytes to the Biomechanical Microenvironment

Articular cartilage and their chondrocytes are physiologically submitted to diverse types of mechanical cues. Chondrocytes produce and maintain the cartilage by sensing and responding to changing mechanical loads. TRPV4 and PIEZOs, activated by mechanical cues, are important mechanosensing molecules...

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Detalles Bibliográficos
Autores principales: Zhang, Min, Meng, Nan, Wang, Xiaoxiao, Chen, Weiyi, Zhang, Quanyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8874592/
https://www.ncbi.nlm.nih.gov/pubmed/35207158
http://dx.doi.org/10.3390/membranes12020237