Cargando…

Assessment of Nasal-Brain-Targeting Efficiency of New Developed Mucoadhesive Emulsomes Encapsulating an Anti-Migraine Drug for Effective Treatment of One of the Major Psychiatric Disorders Symptoms

Migraine is one of the major symptoms of many psychiatric and mental disorders like depression and anxiety. Eletriptan Hydrobromide (EH) is a well-tolerated drug in migraine treatment, but suffers from low oral bioavailability and low brain targeting after oral delivery. New nasal mucoadhesive EH-em...

Descripción completa

Detalles Bibliográficos
Autores principales:	Abo El-Enin, Hadel A., Mostafa, Rasha E., Ahmed, Marwa F., Naguib, Ibrahim A., A. Abdelgawad, Mohamed, Ghoneim, Mohammed M., Abdou, Ebtsam M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8874718/ https://www.ncbi.nlm.nih.gov/pubmed/35214142 http://dx.doi.org/10.3390/pharmaceutics14020410

Ejemplares similares

Lipid Nanocarriers Overlaid with Chitosan for Brain Delivery of Berberine via the Nasal Route
por: Abo El-Enin, Hadel A., et al.
Publicado: (2022)

Targeting Colorectal Cancer Cells with Niosomes Systems Loaded with Two Anticancer Drugs Models; Comparative In Vitro and Anticancer Studies
por: El-Far, Shaymaa Wagdy, et al.
Publicado: (2022)

Formulation and characterization of lamotrigine nasal insert targeted brain for enhanced epilepsy treatment
por: Abdelmonem, Rehab, et al.
Publicado: (2022)

Utilization of Polymeric Micelles as a Lucrative Platform for Efficient Brain Deposition of Olanzapine as an Antischizophrenic Drug via Intranasal Delivery
por: Abo El-Enin, Hadel A., et al.
Publicado: (2022)

Evaluation of Brain Targeting and Antipsychotic Activity of Nasally Administrated Ziprasidone Lipid–Polymer Hybrid Nanocarriers
por: Abo El-Enin, Hadel A., et al.
Publicado: (2023)

S-layer fusion protein as a tool functionalizing emulsomes and CurcuEmulsomes for antibody binding and targeting
por: Ucisik, Mehmet H., et al.
Publicado: (2015)

The Encapsulation of Febuxostat into Emulsomes Strongly Enhances the Cytotoxic Potential of the Drug on HCT 116 Colon Cancer Cells
por: Fahmy, Usama A., et al.
Publicado: (2020)

Repurposing of atorvastatin emulsomes as a topical antifungal agent
por: Eita, Alaa S., et al.
Publicado: (2022)

Nanostructured liquid crystalline formulation as a remarkable new drug delivery system of anti-epileptic drugs for treating children patients
por: El-Enin, Hadel Abo, et al.
Publicado: (2018)

Atorvastatin-loaded emulsomes foam as a topical antifungal formulation
por: Eita, Alaa S., et al.
Publicado: (2022)

A Tailored Thermosensitive PLGA-PEG-PLGA/Emulsomes Composite for Enhanced Oxcarbazepine Brain Delivery via the Nasal Route
por: El-Zaafarany, Ghada M., et al.
Publicado: (2018)

Assessment of the hepatoprotective effect of developed lipid-polymer hybrid nanoparticles (LPHNPs) encapsulating naturally extracted β-Sitosterol against CCl(4) induced hepatotoxicity in rats
por: Abdou, Ebtsam M., et al.
Publicado: (2019)

Nasal Mucoadhesive in situ Gel of Ondansetron Hydrochloride
por: Bhalerao, A. V., et al.
Publicado: (2009)

Quetiapine Albumin Nanoparticles as an Efficacious Platform for Brain Deposition and Potentially Improved Antipsychotic Activity
por: Abdel-Bar, Hend Mohamed, et al.
Publicado: (2023)

Topical delivery of acetazolamide by encapsulating in mucoadhesive nanoparticles
por: Manchanda, Satish, et al.
Publicado: (2017)

Development and evaluation of fixed dose bi therapy sublingual tablets for treatment stress hypertension and anxiety
por: El-Nabarawi, Mohamed A., et al.
Publicado: (2013)

Characterization of CurcuEmulsomes: nanoformulation for enhanced solubility and delivery of curcumin
por: Ucisik, Mehmet H, et al.
Publicado: (2013)

Emulsomes Meet S-layer Proteins: An Emerging Targeted Drug Delivery System
por: Ucisik, Mehmet H., et al.
Publicado: (2015)

Piceatannol-Loaded Emulsomes Exhibit Enhanced Cytostatic and Apoptotic Activities in Colon Cancer Cells
por: Alhakamy, Nabil A., et al.
Publicado: (2020)

Chemical characteristics and targeted encapsulated Cordia myxa fruits extracts nanoparticles for antioxidant and cytotoxicity potentials
por: El-Massry, Khaled F., et al.
Publicado: (2021)

The Application of Mucoadhesive Chitosan Nanoparticles in Nasal Drug Delivery
por: Shim, Soojin, et al.
Publicado: (2020)

Prevalence of using folk medicine and/or natural products in the treatment of hypertension problems compared with medicinal drugs in KSA
por: Aldahhasi, Ghadeer Abdullah, et al.
Publicado: (2022)

Mucoadhesion; A prerequisite or a constraint in nasal drug delivery?
por: Pathak, Kamla
Publicado: (2011)

In-vitro and in-vivo respiratory deposition of a developed metered dose inhaler formulation of an anti-migraine drug
por: Abdou, Ebtsam M., et al.
Publicado: (2019)

Neuroprotective Effects of Curcumin-Loaded Emulsomes in a Laser Axotomy-Induced CNS Injury Model
por: Yilmaz, Elif Nur, et al.
Publicado: (2020)

The Enhanced Cytotoxic and Pro-Apoptotic Effects of Optimized Simvastatin-Loaded Emulsomes on MCF-7 Breast Cancer Cells
por: Awan, Zuhier A., et al.
Publicado: (2020)

A review on mucoadhesive polymer used in nasal drug delivery system
por: Chaturvedi, Mayank, et al.
Publicado: (2011)

A mucoadhesive, thermoreversible in situ nasal gel of geniposide for neurodegenerative diseases
por: Wang, Yingting, et al.
Publicado: (2017)

Toxicity evaluation and nasal mucosal tissue deposition of dexamethasone-infused mucoadhesive in situ nasal gelling systems
por: Pandey, Preeti, et al.
Publicado: (2019)

Preparation and Characterisation of Mucoadhesive Nasal Gel of Venlafaxine Hydrochloride for Treatment of Anxiety Disorders
por: Basu, Shyamoshree, et al.
Publicado: (2012)

Nano-Spray-Dried Levocetirizine Dihydrochloride with Mucoadhesive Carriers and Cyclodextrins for Nasal Administration
por: Mirankó, Mirella, et al.
Publicado: (2023)

Surface-tailoring of emulsomes for boosting brain delivery of vinpocetine via intranasal route: in vitro optimization and in vivo pharmacokinetic assessment
por: Aldawsari, Hibah M., et al.
Publicado: (2022)

Possible Role of Ivermectin Mucoadhesive Nanosuspension Nasal Spray in Recovery of Post-COVID-19 Anosmia
por: Aref, Zaki F, et al.
Publicado: (2022)

Effect of Fentanyl Addition to Local Anaesthetic in Peribulbar Block
por: Abo El Enin, Mostafa Abdel Hamid, et al.
Publicado: (2009)

Intra Nasal In situ Gelling System of Lamotrigine Using Ion Activated Mucoadhesive Polymer
por: Paul, Asha, et al.
Publicado: (2017)

Design and statistical optimisation of emulsomal nanoparticles for improved anti-SARS-CoV-2 activity of N-(5-nitrothiazol-2-yl)-carboxamido candidates: in vitro and in silico studies
por: Al-Karmalawy, Ahmed A., et al.
Publicado: (2023)

Lyophilized Chitosan/xanthan Polyelectrolyte Complex Based Mucoadhesive Inserts for Nasal Delivery of Promethazine Hydrochloride
por: G Dehghan, Mohamed Hassan, et al.
Publicado: (2014)

Preparation and In Vitro Characterization of Mucoadhesive Hydroxypropyl Guar Microspheres Containing Amlodipine Besylate for Nasal Administration
por: Swamy, N. G. N., et al.
Publicado: (2011)

Sinonasal Delivery of Resveratrol via Mucoadhesive Nanostructured Microparticles in a Nasal Polyp Mouse Model
por: Lee, Mingyu, et al.
Publicado: (2017)

Enhanced Nasal Deposition and Anti-Coronavirus Effect of Favipiravir-Loaded Mucoadhesive Chitosan–Alginate Nanoparticles
por: Alcantara, Khent Primo, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_t00tqq4n8q9hil6ovuen4uklvv