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Influence of Random Plasmonic Metasurfaces on Fluorescence Enhancement

One of the strategies employed to increase the sensitivity of the fluorescence-based biosensors is to deposit chromophores on plasmonic metasurfaces which are periodic arrays of resonating nano-antennas that allow the control of the electromagnetic field leading to fluorescence enhancement. While ar...

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Autores principales: Anăstăsoaie, Veronica, Tomescu, Roxana, Kusko, Cristian, Mihalache, Iuliana, Dinescu, Adrian, Parvulescu, Catalin, Craciun, Gabriel, Caramizoiu, Stefan, Cristea, Dana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8874827/
https://www.ncbi.nlm.nih.gov/pubmed/35207970
http://dx.doi.org/10.3390/ma15041429
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author Anăstăsoaie, Veronica
Tomescu, Roxana
Kusko, Cristian
Mihalache, Iuliana
Dinescu, Adrian
Parvulescu, Catalin
Craciun, Gabriel
Caramizoiu, Stefan
Cristea, Dana
author_facet Anăstăsoaie, Veronica
Tomescu, Roxana
Kusko, Cristian
Mihalache, Iuliana
Dinescu, Adrian
Parvulescu, Catalin
Craciun, Gabriel
Caramizoiu, Stefan
Cristea, Dana
author_sort Anăstăsoaie, Veronica
collection PubMed
description One of the strategies employed to increase the sensitivity of the fluorescence-based biosensors is to deposit chromophores on plasmonic metasurfaces which are periodic arrays of resonating nano-antennas that allow the control of the electromagnetic field leading to fluorescence enhancement. While artificially engineered metasurfaces realized by micro/nano-fabrication techniques lead to a precise tailoring of the excitation field and resonant cavity properties, the technological overhead, small areas, and high manufacturing cost renders them unsuitable for mass production. A method to circumvent these challenges is to use random distribution of metallic nanoparticles sustaining plasmonic resonances, which present the properties required to significantly enhance the fluorescence. We investigate metasurfaces composed of random aggregates of metal nanoparticles deposited on a silicon and glass substrates. The finite difference time domain simulations of the interaction of the incident electromagnetic wave with the structures reveals a significant enhancement of the excitation field, which is due to the resonant plasmonic modes sustained by the nanoparticles aggregates. We experimentally investigated the role of these structures in the fluorescent behaviour of Rhodamine 6G dispersed in polymethylmethacrylate finding an enhancement that is 423-fold. This suggests that nanoparticle aggregates have the potential to constitute a suitable platform for low-cost, mass-produced fluorescent biosensors.
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spelling pubmed-88748272022-02-26 Influence of Random Plasmonic Metasurfaces on Fluorescence Enhancement Anăstăsoaie, Veronica Tomescu, Roxana Kusko, Cristian Mihalache, Iuliana Dinescu, Adrian Parvulescu, Catalin Craciun, Gabriel Caramizoiu, Stefan Cristea, Dana Materials (Basel) Article One of the strategies employed to increase the sensitivity of the fluorescence-based biosensors is to deposit chromophores on plasmonic metasurfaces which are periodic arrays of resonating nano-antennas that allow the control of the electromagnetic field leading to fluorescence enhancement. While artificially engineered metasurfaces realized by micro/nano-fabrication techniques lead to a precise tailoring of the excitation field and resonant cavity properties, the technological overhead, small areas, and high manufacturing cost renders them unsuitable for mass production. A method to circumvent these challenges is to use random distribution of metallic nanoparticles sustaining plasmonic resonances, which present the properties required to significantly enhance the fluorescence. We investigate metasurfaces composed of random aggregates of metal nanoparticles deposited on a silicon and glass substrates. The finite difference time domain simulations of the interaction of the incident electromagnetic wave with the structures reveals a significant enhancement of the excitation field, which is due to the resonant plasmonic modes sustained by the nanoparticles aggregates. We experimentally investigated the role of these structures in the fluorescent behaviour of Rhodamine 6G dispersed in polymethylmethacrylate finding an enhancement that is 423-fold. This suggests that nanoparticle aggregates have the potential to constitute a suitable platform for low-cost, mass-produced fluorescent biosensors. MDPI 2022-02-15 /pmc/articles/PMC8874827/ /pubmed/35207970 http://dx.doi.org/10.3390/ma15041429 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Anăstăsoaie, Veronica
Tomescu, Roxana
Kusko, Cristian
Mihalache, Iuliana
Dinescu, Adrian
Parvulescu, Catalin
Craciun, Gabriel
Caramizoiu, Stefan
Cristea, Dana
Influence of Random Plasmonic Metasurfaces on Fluorescence Enhancement
title Influence of Random Plasmonic Metasurfaces on Fluorescence Enhancement
title_full Influence of Random Plasmonic Metasurfaces on Fluorescence Enhancement
title_fullStr Influence of Random Plasmonic Metasurfaces on Fluorescence Enhancement
title_full_unstemmed Influence of Random Plasmonic Metasurfaces on Fluorescence Enhancement
title_short Influence of Random Plasmonic Metasurfaces on Fluorescence Enhancement
title_sort influence of random plasmonic metasurfaces on fluorescence enhancement
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8874827/
https://www.ncbi.nlm.nih.gov/pubmed/35207970
http://dx.doi.org/10.3390/ma15041429
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