Transgenerational Transcriptomic and DNA Methylome Profiling of Mouse Fetal Testicular Germline and Somatic Cells after Exposure of Pregnant Mothers to Tributyltin, a Potent Obesogen

Obesogens such as tributyltin (TBT) are xenobiotic compounds that promote obesity, in part by distorting the normal balance of lipid metabolism. The obesogenic effects of TBT can be observed in directly exposed (F1 and F2 generations) and also subsequent generations (F3 and beyond) that were never e...

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Detalles Bibliográficos
Autores principales: Shioda, Keiko, Odajima, Junko, Blumberg, Bruce, Shioda, Toshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8874857/
https://www.ncbi.nlm.nih.gov/pubmed/35208169
http://dx.doi.org/10.3390/metabo12020095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8874857/
https://www.ncbi.nlm.nih.gov/pubmed/35208169
http://dx.doi.org/10.3390/metabo12020095

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