Cargando…

Kaposi’s Sarcoma Lesion Progression in BKV-Tat Transgenic Mice Is Increased by Inflammatory Cytokines and Blocked by Treatment with Anti-Tat Antibodies

Kaposi’s sarcoma (KS) is an angioproliferative tumor showing an increased frequency and aggressiveness in HIV-infected subjects (AIDS-KS), due to the combined effects of inflammatory cytokines (IC), angiogenic factors, and the HIV-1 Tat protein. While the introduction of effective combined antiretro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Brocca-Cofano, Egidio, Sgadari, Cecilia, Picconi, Orietta, Palladino, Clelia, Caputo, Antonella, Ensoli, Barbara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8874961/ https://www.ncbi.nlm.nih.gov/pubmed/35216197 http://dx.doi.org/10.3390/ijms23042081

Ejemplares similares

Anti-Tat Immunity in HIV-1 Infection: Effects of Naturally Occurring and Vaccine-Induced Antibodies Against Tat on the Course of the Disease
por: Cafaro, Aurelio, et al.
Publicado: (2019)

Fibroblast Growth Factor-2 and the HIV-1 Tat Protein Synergize in Promoting Bcl-2 Expression and Preventing Endothelial Cell Apoptosis: Implications for the Pathogenesis of AIDS-Associated Kaposi's Sarcoma
por: Sgadari, Cecilia, et al.
Publicado: (2011)

New insights into pathogenesis point to HIV-1 Tat as a key vaccine target
por: Ensoli, Barbara, et al.
Publicado: (2021)

HIV-1 Tat Protein Enters Dysfunctional Endothelial Cells via Integrins and Renders Them Permissive to Virus Replication
por: Cafaro, Aurelio, et al.
Publicado: (2020)

Anti-Tat immunity defines CD4(+) T-cell dynamics in people living with HIV on long-term cART.
por: Tripiciano, Antonella, et al.
Publicado: (2021)

Inflammatory angiogenesis as a target for prevention and therapy: Kaposi's sarcoma and HIV tat as models
por: Albini, Adriana, et al.
Publicado: (2006)

Continued Decay of HIV Proviral DNA Upon Vaccination With HIV-1 Tat of Subjects on Long-Term ART: An 8-Year Follow-Up Study
por: Sgadari, Cecilia, et al.
Publicado: (2019)

Entrance of the Tat protein of HIV-1 into human uterine cervical carcinoma cells causes upregulation of HPV-E6 expression and a decrease in p53 protein levels
por: Barillari, Giovanni, et al.
Publicado: (2016)

HIV-Tat immunization induces cross-clade neutralizing antibodies and CD4(+) T cell increases in antiretroviral-treated South African volunteers: a randomized phase II clinical trial
por: Ensoli, Barbara, et al.
Publicado: (2016)

TatBC-Independent TatA/Tat Substrate Interactions Contribute to Transport Efficiency
por: Taubert, Johannes, et al.
Publicado: (2015)

HIV-1 Tat Promotes Integrin-Mediated HIV Transmission to Dendritic Cells by Binding Env Spikes and Competes Neutralization by Anti-HIV Antibodies
por: Monini, Paolo, et al.
Publicado: (2012)

How to achieve Tat transport with alien TatA
por: Hauer, René Steffen, et al.
Publicado: (2017)

HIV-1 Tat immunization restores immune homeostasis and attacks the HAART-resistant blood HIV DNA: results of a randomized phase II exploratory clinical trial
por: Ensoli, Fabrizio, et al.
Publicado: (2015)

Substrate-triggered position switching of TatA and TatB during Tat transport in Escherichia coli
por: Habersetzer, Johann, et al.
Publicado: (2017)

The presence of anti-Tat antibodies in HIV-infected individuals is associated with containment of CD4(+) T-cell decay and viral load, and with delay of disease progression: results of a 3-year cohort study
por: Bellino, Stefania, et al.
Publicado: (2014)

Comparative Analysis of Tat-Dependent and Tat-Deficient Natural Lentiviruses
por: Bose, Deepanwita, et al.
Publicado: (2015)

The Tat Protein of HIV-1 Prevents the Loss of HSV-Specific Memory Adaptive Responses and Favors the Control of Viral Reactivation
por: Nicoli, Francesco, et al.
Publicado: (2020)

TatA and TatB generate a hydrophobic mismatch important for the function and assembly of the Tat translocon in Escherichia coli
por: Mehner-Breitfeld, Denise, et al.
Publicado: (2022)

Herpes Simplex Virus Type 2 Triggers Reactivation of Kaposi's Sarcoma-Associated Herpesvirus from Latency and Collaborates with HIV-1 Tat
por: Tang, Qiao, et al.
Publicado: (2012)

Characterization of a TatA/TatB binding site on the TatC component of the Escherichia coli twin arginine translocase
por: Severi, Emmanuele, et al.
Publicado: (2023)

A reversal of Tat
por: Tuma, Rabiya S.
Publicado: (2005)

The two sides of Tat
por: Barboric, Matjaz, et al.
Publicado: (2016)

The HIV-1 Tat Protein Induces the Activation of CD8(+) T Cells and Affects In Vivo the Magnitude and Kinetics of Antiviral Responses
por: Nicoli, Francesco, et al.
Publicado: (2013)

TatB Functions as an Oligomeric Binding Site for Folded Tat Precursor Proteins
por: Maurer, Carlo, et al.
Publicado: (2010)

Mechanism of HIV-1 Tat RNA translation and its activation by the Tat protein
por: Charnay, Nicolas, et al.
Publicado: (2009)

Molecular dissection of TatC defines critical regions essential for protein transport and a TatB–TatC contact site
por: Kneuper, Holger, et al.
Publicado: (2012)

TatBC, TatB, and TatC form structurally autonomous units within the twin arginine protein transport system of Escherichia coli
por: Orriss, George L., et al.
Publicado: (2007)

Unanticipated functional diversity among the TatA-type components of the Tat protein translocase
por: Eimer, Ekaterina, et al.
Publicado: (2018)

New insights into the Tat protein transport cycle from characterizing the assembled Tat translocon
por: Alcock, Felicity, et al.
Publicado: (2022)

Therapeutic Immunization with HIV-1 Tat Reduces Immune Activation and Loss of Regulatory T-Cells and Improves Immune Function in Subjects on HAART
por: Ensoli, Barbara, et al.
Publicado: (2010)

Genetic Evidence for a Tight Cooperation of TatB and TatC during Productive Recognition of Twin-Arginine (Tat) Signal Peptides in Escherichia coli
por: Lausberg, Frank, et al.
Publicado: (2012)

Tat substrates open the portal
por: Short, Ben
Publicado: (2014)

Sec and Tat share the workload
por: Short, Ben
Publicado: (2012)

Assembling the Tat protein translocase
por: Alcock, Felicity, et al.
Publicado: (2016)

The Tat and Cat in Clinical Use
por: Franks, Cyril M.
Publicado: (1955)

From ESMO TAT 2021
por: Killock, David
Publicado: (2021)

Modulation of microtubule assembly by the HIV-1 Tat protein is strongly dependent on zinc binding to Tat
por: Egelé, Caroline, et al.
Publicado: (2008)

Dynamic interactions of the HIV-1 Tat with nucleic acids are critical for Tat activity in reverse transcription
por: Boudier, Christian, et al.
Publicado: (2014)

Twin-Arginine Translocation System in Helicobacter pylori: TatC, but Not TatB, Is Essential for Viability
por: Benoit, Stéphane L., et al.
Publicado: (2014)

Transmembrane insertion of twin-arginine signal peptides is driven by TatC and regulated by TatB
por: Fröbel, Julia, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_pg60ph8qj3d7obgk91sok5m74t