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Vitamin D Status and Health Outcomes in School Children in Northern Ireland: Year One Results from the D-VinCHI Study

(1) Background: Vitamin D status has never been investigated in children in Northern Ireland (UK). (2) Methods: Children (4–11 years) (n = 47) were recruited from November 2019 to March 2020 onto the cross-sectional study. Anthropometry was assessed. Plasma 25-hydroxyvitamin D (25(OH)D) was analysed...

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Autores principales: Glatt, Dominique Ulrike, McSorley, Emeir, Pourshahidi, L. Kirsty, Revuelta Iniesta, Raquel, McCluskey, Jane, Beggan, Laura, Slevin, Mary, Gleeson, Nigel, Cobice, Diego F., Dobbin, Sara, Magee, Pamela J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875093/
https://www.ncbi.nlm.nih.gov/pubmed/35215452
http://dx.doi.org/10.3390/nu14040804
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author Glatt, Dominique Ulrike
McSorley, Emeir
Pourshahidi, L. Kirsty
Revuelta Iniesta, Raquel
McCluskey, Jane
Beggan, Laura
Slevin, Mary
Gleeson, Nigel
Cobice, Diego F.
Dobbin, Sara
Magee, Pamela J.
author_facet Glatt, Dominique Ulrike
McSorley, Emeir
Pourshahidi, L. Kirsty
Revuelta Iniesta, Raquel
McCluskey, Jane
Beggan, Laura
Slevin, Mary
Gleeson, Nigel
Cobice, Diego F.
Dobbin, Sara
Magee, Pamela J.
author_sort Glatt, Dominique Ulrike
collection PubMed
description (1) Background: Vitamin D status has never been investigated in children in Northern Ireland (UK). (2) Methods: Children (4–11 years) (n = 47) were recruited from November 2019 to March 2020 onto the cross-sectional study. Anthropometry was assessed. Plasma 25-hydroxyvitamin D (25(OH)D) was analysed. Vitamin D intake, parental knowledge and perceptions, participant habits, physical activity and sedentary behaviour were established via questionnaire. Muscle strength was assessed via isometric grip strength dynamometry and balance via dominant single-leg and tandem stance. Parathyroid hormone, bone turnover markers (OC, CTX and P1NP), glycated haemoglobin and inflammatory markers (CRP, IFN-γ, IL-10, IL-12p70, IL-13, IL-1β, IL-2, IL-4, IL-6, IL-8 and TNF-α) were analysed. (3) Results: Mean (SD) 25(OH)D was 49.17 (17.04) nmol/L (n = 47); 44.7% of the children were vitamin D sufficient (25(OH)D >50 nmol/L), 48.9% were insufficient (25–50 nmol/L) and 6.4% were deficient (<25 nmol/L). 25(OH)D was positively correlated with vitamin D intake (µg/day) (p = 0.012, r = 0.374), spring/summer outdoor hours (p = 0.006, r = 0.402) and dominant grip strength (kg) (p = 0.044, r = 0.317). Vitamin D sufficient participants had higher dietary vitamin D intake (µg/day) (p = 0.021), supplement intake (µg/day) (p = 0.028) and spring/summer outdoor hours (p = 0.015). (4) Conclusion: Over half of the children were vitamin D deficient or insufficient. Wintertime supplementation, the consumption of vitamin D rich foods and spring/summer outdoor activities should be encouraged to minimise the risk of vitamin D inadequacy.
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spelling pubmed-88750932022-02-26 Vitamin D Status and Health Outcomes in School Children in Northern Ireland: Year One Results from the D-VinCHI Study Glatt, Dominique Ulrike McSorley, Emeir Pourshahidi, L. Kirsty Revuelta Iniesta, Raquel McCluskey, Jane Beggan, Laura Slevin, Mary Gleeson, Nigel Cobice, Diego F. Dobbin, Sara Magee, Pamela J. Nutrients Article (1) Background: Vitamin D status has never been investigated in children in Northern Ireland (UK). (2) Methods: Children (4–11 years) (n = 47) were recruited from November 2019 to March 2020 onto the cross-sectional study. Anthropometry was assessed. Plasma 25-hydroxyvitamin D (25(OH)D) was analysed. Vitamin D intake, parental knowledge and perceptions, participant habits, physical activity and sedentary behaviour were established via questionnaire. Muscle strength was assessed via isometric grip strength dynamometry and balance via dominant single-leg and tandem stance. Parathyroid hormone, bone turnover markers (OC, CTX and P1NP), glycated haemoglobin and inflammatory markers (CRP, IFN-γ, IL-10, IL-12p70, IL-13, IL-1β, IL-2, IL-4, IL-6, IL-8 and TNF-α) were analysed. (3) Results: Mean (SD) 25(OH)D was 49.17 (17.04) nmol/L (n = 47); 44.7% of the children were vitamin D sufficient (25(OH)D >50 nmol/L), 48.9% were insufficient (25–50 nmol/L) and 6.4% were deficient (<25 nmol/L). 25(OH)D was positively correlated with vitamin D intake (µg/day) (p = 0.012, r = 0.374), spring/summer outdoor hours (p = 0.006, r = 0.402) and dominant grip strength (kg) (p = 0.044, r = 0.317). Vitamin D sufficient participants had higher dietary vitamin D intake (µg/day) (p = 0.021), supplement intake (µg/day) (p = 0.028) and spring/summer outdoor hours (p = 0.015). (4) Conclusion: Over half of the children were vitamin D deficient or insufficient. Wintertime supplementation, the consumption of vitamin D rich foods and spring/summer outdoor activities should be encouraged to minimise the risk of vitamin D inadequacy. MDPI 2022-02-14 /pmc/articles/PMC8875093/ /pubmed/35215452 http://dx.doi.org/10.3390/nu14040804 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Glatt, Dominique Ulrike
McSorley, Emeir
Pourshahidi, L. Kirsty
Revuelta Iniesta, Raquel
McCluskey, Jane
Beggan, Laura
Slevin, Mary
Gleeson, Nigel
Cobice, Diego F.
Dobbin, Sara
Magee, Pamela J.
Vitamin D Status and Health Outcomes in School Children in Northern Ireland: Year One Results from the D-VinCHI Study
title Vitamin D Status and Health Outcomes in School Children in Northern Ireland: Year One Results from the D-VinCHI Study
title_full Vitamin D Status and Health Outcomes in School Children in Northern Ireland: Year One Results from the D-VinCHI Study
title_fullStr Vitamin D Status and Health Outcomes in School Children in Northern Ireland: Year One Results from the D-VinCHI Study
title_full_unstemmed Vitamin D Status and Health Outcomes in School Children in Northern Ireland: Year One Results from the D-VinCHI Study
title_short Vitamin D Status and Health Outcomes in School Children in Northern Ireland: Year One Results from the D-VinCHI Study
title_sort vitamin d status and health outcomes in school children in northern ireland: year one results from the d-vinchi study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875093/
https://www.ncbi.nlm.nih.gov/pubmed/35215452
http://dx.doi.org/10.3390/nu14040804
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