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Torque Teno Sus Virus (TTSuV) Prevalence in Wild Fauna of Northern Italy
Torque teno sus virus (TTSuV) is a non-enveloped circular ssDNA virus which frequently infects swine and has been associated with hepatic, respiratory, and autoimmune disorders. TTSuV’s pathogenic role is still uncertain, and clear data in the literature on virus reservoirs are lacking. The aims of...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875128/ https://www.ncbi.nlm.nih.gov/pubmed/35208696 http://dx.doi.org/10.3390/microorganisms10020242 |
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author | Righi, Francesco Arnaboldi, Sara Filipello, Virginia Ianiro, Giovanni Di Bartolo, Ilaria Calò, Stefania Bellini, Silvia Trogu, Tiziana Lelli, Davide Bianchi, Alessandro Bonardi, Silvia Pavoni, Enrico Bertasi, Barbara Lavazza, Antonio |
author_facet | Righi, Francesco Arnaboldi, Sara Filipello, Virginia Ianiro, Giovanni Di Bartolo, Ilaria Calò, Stefania Bellini, Silvia Trogu, Tiziana Lelli, Davide Bianchi, Alessandro Bonardi, Silvia Pavoni, Enrico Bertasi, Barbara Lavazza, Antonio |
author_sort | Righi, Francesco |
collection | PubMed |
description | Torque teno sus virus (TTSuV) is a non-enveloped circular ssDNA virus which frequently infects swine and has been associated with hepatic, respiratory, and autoimmune disorders. TTSuV’s pathogenic role is still uncertain, and clear data in the literature on virus reservoirs are lacking. The aims of this study were to investigate the presence of potentially zoonotic TTSuV in wild animals in Northern Italy and to evaluate their role as reservoirs. Liver samples were collected between 2016 and 2020 during four hunting seasons from wild boars (Sus scrofa), red deer (Cervus elaphus), roe deer (Capreolus capreolus), and chamois (Rupicapra rupicapra). Samples originated from areas in Northern Italy characterized by different traits, i.e., mountains and flatland with, respectively low and high farm density and anthropization. Viral identification was carried out by end-point PCR with specific primers for TTSuV1a and TTSuVk2a species. TTSuV prevalence in wild boars was higher in the mountains than in the flatland (prevalence of 6.2% and 2.3%, respectively). In wild ruminants only TTSuVk2a was detected (with a prevalence of 9.4%). Our findings shed light on the occurrence and distribution of TTSuV in some wild animal species, investigating their possible role as reservoirs. |
format | Online Article Text |
id | pubmed-8875128 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-88751282022-02-26 Torque Teno Sus Virus (TTSuV) Prevalence in Wild Fauna of Northern Italy Righi, Francesco Arnaboldi, Sara Filipello, Virginia Ianiro, Giovanni Di Bartolo, Ilaria Calò, Stefania Bellini, Silvia Trogu, Tiziana Lelli, Davide Bianchi, Alessandro Bonardi, Silvia Pavoni, Enrico Bertasi, Barbara Lavazza, Antonio Microorganisms Article Torque teno sus virus (TTSuV) is a non-enveloped circular ssDNA virus which frequently infects swine and has been associated with hepatic, respiratory, and autoimmune disorders. TTSuV’s pathogenic role is still uncertain, and clear data in the literature on virus reservoirs are lacking. The aims of this study were to investigate the presence of potentially zoonotic TTSuV in wild animals in Northern Italy and to evaluate their role as reservoirs. Liver samples were collected between 2016 and 2020 during four hunting seasons from wild boars (Sus scrofa), red deer (Cervus elaphus), roe deer (Capreolus capreolus), and chamois (Rupicapra rupicapra). Samples originated from areas in Northern Italy characterized by different traits, i.e., mountains and flatland with, respectively low and high farm density and anthropization. Viral identification was carried out by end-point PCR with specific primers for TTSuV1a and TTSuVk2a species. TTSuV prevalence in wild boars was higher in the mountains than in the flatland (prevalence of 6.2% and 2.3%, respectively). In wild ruminants only TTSuVk2a was detected (with a prevalence of 9.4%). Our findings shed light on the occurrence and distribution of TTSuV in some wild animal species, investigating their possible role as reservoirs. MDPI 2022-01-22 /pmc/articles/PMC8875128/ /pubmed/35208696 http://dx.doi.org/10.3390/microorganisms10020242 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Righi, Francesco Arnaboldi, Sara Filipello, Virginia Ianiro, Giovanni Di Bartolo, Ilaria Calò, Stefania Bellini, Silvia Trogu, Tiziana Lelli, Davide Bianchi, Alessandro Bonardi, Silvia Pavoni, Enrico Bertasi, Barbara Lavazza, Antonio Torque Teno Sus Virus (TTSuV) Prevalence in Wild Fauna of Northern Italy |
title | Torque Teno Sus Virus (TTSuV) Prevalence in Wild Fauna of Northern Italy |
title_full | Torque Teno Sus Virus (TTSuV) Prevalence in Wild Fauna of Northern Italy |
title_fullStr | Torque Teno Sus Virus (TTSuV) Prevalence in Wild Fauna of Northern Italy |
title_full_unstemmed | Torque Teno Sus Virus (TTSuV) Prevalence in Wild Fauna of Northern Italy |
title_short | Torque Teno Sus Virus (TTSuV) Prevalence in Wild Fauna of Northern Italy |
title_sort | torque teno sus virus (ttsuv) prevalence in wild fauna of northern italy |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875128/ https://www.ncbi.nlm.nih.gov/pubmed/35208696 http://dx.doi.org/10.3390/microorganisms10020242 |
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