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Interaction and Compatibility Studies in the Development of Olmesartan Medoxomil and Hydrochlorothiazide Formulations under a Real Manufacturing Process
A drug–drug and drug–excipient interactions and compatibilities study was conducted for two fixed-dose combination (FDC) products containing olmesartan medoxomil (OLM)/hydrochlorothiazide (HCT) 20/12.5 mg and OLM/HCT 40/12.5 mg during their development including storage. The study consisted of the e...
Autores principales: | Murillo-Fernández, Mac Arturo, Montero-Zeledón, Ernesto, Abdala-Saiz, Ariadna, Vega-Baudrit, José Roberto, Araya-Sibaja, Andrea Mariela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875139/ https://www.ncbi.nlm.nih.gov/pubmed/35214156 http://dx.doi.org/10.3390/pharmaceutics14020424 |
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