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The Study of Microbe–Host Two-Way Communication
Back-and-forth intercommunication in host–pathogen interactions has long been recognized to play an important role in commensalism and microbial pathogenesis. For centuries, we have studied these microbes in our surroundings, yet many questions about the evolutionary cross-talk between host and micr...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875206/ https://www.ncbi.nlm.nih.gov/pubmed/35208862 http://dx.doi.org/10.3390/microorganisms10020408 |
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author | Perry, Famatta Arsenault, Ryan J. |
author_facet | Perry, Famatta Arsenault, Ryan J. |
author_sort | Perry, Famatta |
collection | PubMed |
description | Back-and-forth intercommunication in host–pathogen interactions has long been recognized to play an important role in commensalism and microbial pathogenesis. For centuries, we have studied these microbes in our surroundings, yet many questions about the evolutionary cross-talk between host and microbe remain unanswered. With the recent surge in research interest in the commensal microbiome, basic immunological questions have returned to the fore, such as, how are vast numbers of microbes capable of coexisting within animals and humans while also maintaining a healthy functional immune system? How is the evasion and subversion of the immune system achieved by some microbes but not others? The intricate and important-to-remember two-way interaction and coevolution of host and microbe is the communication network we must tap into as researchers to answer these questions. |
format | Online Article Text |
id | pubmed-8875206 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-88752062022-02-26 The Study of Microbe–Host Two-Way Communication Perry, Famatta Arsenault, Ryan J. Microorganisms Perspective Back-and-forth intercommunication in host–pathogen interactions has long been recognized to play an important role in commensalism and microbial pathogenesis. For centuries, we have studied these microbes in our surroundings, yet many questions about the evolutionary cross-talk between host and microbe remain unanswered. With the recent surge in research interest in the commensal microbiome, basic immunological questions have returned to the fore, such as, how are vast numbers of microbes capable of coexisting within animals and humans while also maintaining a healthy functional immune system? How is the evasion and subversion of the immune system achieved by some microbes but not others? The intricate and important-to-remember two-way interaction and coevolution of host and microbe is the communication network we must tap into as researchers to answer these questions. MDPI 2022-02-10 /pmc/articles/PMC8875206/ /pubmed/35208862 http://dx.doi.org/10.3390/microorganisms10020408 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Perspective Perry, Famatta Arsenault, Ryan J. The Study of Microbe–Host Two-Way Communication |
title | The Study of Microbe–Host Two-Way Communication |
title_full | The Study of Microbe–Host Two-Way Communication |
title_fullStr | The Study of Microbe–Host Two-Way Communication |
title_full_unstemmed | The Study of Microbe–Host Two-Way Communication |
title_short | The Study of Microbe–Host Two-Way Communication |
title_sort | study of microbe–host two-way communication |
topic | Perspective |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875206/ https://www.ncbi.nlm.nih.gov/pubmed/35208862 http://dx.doi.org/10.3390/microorganisms10020408 |
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