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DDX50 Is a Viral Restriction Factor That Enhances IRF3 Activation
The transcription factors IRF3 and NF-κB are crucial in innate immune signalling in response to many viral and bacterial pathogens. However, mechanisms leading to their activation remain incompletely understood. Viral RNA can be detected by RLR receptors, such as RIG-I and MDA5, and the dsRNA recept...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875258/ https://www.ncbi.nlm.nih.gov/pubmed/35215908 http://dx.doi.org/10.3390/v14020316 |