Down-Regulation of C1GALT1 Enhances the Progression of Cholangiocarcinoma through Activation of AKT/ERK Signaling Pathways

Alteration of mucin-type O-glycosylation is implicated in tumor progression and metastasis of cholangiocarcinoma (CCA). Core 1 β1-3 Galactosyltransferase (C1GALT1) is a primary enzyme that regulates the elongation of core 1-derived mucin-type O-glycans. Dysregulation of C1GALT1 has been documented i...

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Detalles Bibliográficos
Autores principales: Khiaowichit, Juthamas, Talabnin, Chutima, Dechsukhum, Chavaboon, Silsirivanit, Atit, Talabnin, Krajang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875272/
https://www.ncbi.nlm.nih.gov/pubmed/35207462
http://dx.doi.org/10.3390/life12020174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875272/
https://www.ncbi.nlm.nih.gov/pubmed/35207462
http://dx.doi.org/10.3390/life12020174

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