An Essential Role for Alzheimer’s-Linked Amyloid Beta Oligomers in Neurodevelopment: Transient Expression of Multiple Proteoforms during Retina Histogenesis

Human amyloid beta peptide (Aβ) is a brain catabolite that at nanomolar concentrations can form neurotoxic oligomers (AβOs), which are known to accumulate in Alzheimer’s disease. Because a predisposition to form neurotoxins seems surprising, we have investigated whether circumstances might exist whe...

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Detalles Bibliográficos
Autores principales: Bartley, Samuel C., Proctor, Madison T., Xia, Hongjie, Ho, Evelyn, Kang, Dong S., Schuster, Kristen, Bicca, Maíra A., Seckler, Henrique S., Viola, Kirsten L., Patrie, Steven M., Kelleher, Neil L., De Mello, Fernando G., Klein, William L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875314/
https://www.ncbi.nlm.nih.gov/pubmed/35216328
http://dx.doi.org/10.3390/ijms23042208

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