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Capturing a Crucial ‘Disorder-to-Order Transition’ at the Heart of the Coronavirus Molecular Pathology—Triggered by Highly Persistent, Interchangeable Salt-Bridges

The COVID-19 origin debate has greatly been influenced by genome comparison studies of late, revealing the emergence of the Furin-like cleavage site at the S1/S2 junction of the SARS-CoV-2 Spike (FLCS(Spike)) containing its (681)PRRAR(685) motif, absent in other related respiratory viruses. Being th...

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Detalles Bibliográficos
Autores principales: Roy, Sourav, Ghosh, Prithwi, Bandyopadhyay, Abhirup, Basu, Sankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875383/
https://www.ncbi.nlm.nih.gov/pubmed/35214759
http://dx.doi.org/10.3390/vaccines10020301