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The Influence of Circadian Rhythm on Cancer Cells Targeting and Transfection Efficiency of a Polycation-Drug/Gene Delivery Vector

The conception of novel anticancer delivery systems and the combination of chronobiology with nanotechnology may provide a powerful tool to optimize cancer therapy. In this work, polyethylenimine (PEI) has been used to complex p53 encoded plasmid DNA (pDNA), and the anticancer drug methotrexate (MTX...

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Detalles Bibliográficos
Autores principales:	Albuquerque, Tânia, Neves, Ana R., Quintela, Telma, Costa, Diana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875434/ https://www.ncbi.nlm.nih.gov/pubmed/35215593 http://dx.doi.org/10.3390/polym14040681

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