A Novel Peptide Derived from Arca inflata Induces Apoptosis in Colorectal Cancer Cells through Mitochondria and the p38 MAPK Pathway

Colorectal carcinoma (CRC) is one of the major causes of cancer-related incidence and deaths. Here, we identified a novel antitumor peptide, P6, with a molecular weight of 2794.8 Da from a marine Chinese medicine, Arca inflata Reeve. The full amino acid sequence and secondary structure of P6 were de...

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Detalles Bibliográficos
Autores principales: Li, Chunlei, Zhang, Sirui, Zhu, Jianhua, Huang, Weijuan, Luo, Yuanyuan, Shi, Hui, Yu, Dongbo, Chen, Liguo, Song, Liyan, Yu, Rongmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875476/
https://www.ncbi.nlm.nih.gov/pubmed/35200639
http://dx.doi.org/10.3390/md20020110

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