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Generation and Characterization of a Zebrafish IL-2Rγc SCID Model

The IL-2 family of cytokines act via receptor complexes that share the interleukin-2 receptor gamma common (IL-2Rγc) chain to play key roles in lymphopoiesis. Inactivating IL-2Rγc mutations results in severe combined immunodeficiency (SCID) in humans and other species. This study sought to generate...

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Detalles Bibliográficos
Autores principales:	Sertori, Robert, Jones, Realla, Basheer, Faiza, Rivera, Leni, Dawson, Samantha, Loke, Stella, Heidary, Somayyeh, Dhillon, Amardeep, Liongue, Clifford, Ward, Alister C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875600/ https://www.ncbi.nlm.nih.gov/pubmed/35216498 http://dx.doi.org/10.3390/ijms23042385

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