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Plant Extract-Synthesized Silver Nanoparticles for Application in Dental Therapy

Oral diseases are the most common non-communicable diseases in the world, with dental caries and periodontitis causing major health and social problems. These diseases can progress to systematic diseases and cause disfigurement when left untreated. However, treatment of oral diseases is among the mo...

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Autores principales: Ahmed, Omnia, Sibuyi, Nicole Remaliah Samantha, Fadaka, Adewale Oluwaseun, Madiehe, Madimabe Abram, Maboza, Ernest, Meyer, Mervin, Geerts, Greta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875651/
https://www.ncbi.nlm.nih.gov/pubmed/35214112
http://dx.doi.org/10.3390/pharmaceutics14020380
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author Ahmed, Omnia
Sibuyi, Nicole Remaliah Samantha
Fadaka, Adewale Oluwaseun
Madiehe, Madimabe Abram
Maboza, Ernest
Meyer, Mervin
Geerts, Greta
author_facet Ahmed, Omnia
Sibuyi, Nicole Remaliah Samantha
Fadaka, Adewale Oluwaseun
Madiehe, Madimabe Abram
Maboza, Ernest
Meyer, Mervin
Geerts, Greta
author_sort Ahmed, Omnia
collection PubMed
description Oral diseases are the most common non-communicable diseases in the world, with dental caries and periodontitis causing major health and social problems. These diseases can progress to systematic diseases and cause disfigurement when left untreated. However, treatment of oral diseases is among the most expensive treatments and often focus on restoration of form and function. Caries prevention has traditionally relied on oral hygiene and diet control, among other preventive measures. In this paper, these measures are not disqualified but are brought into a new context through the use of nanotechnology-based materials to improve these conventional therapeutic and preventive measures. Among inorganic nanomaterials, silver nanoparticles (AgNPs) have shown promising outcomes in dental therapy, due to their unique physicochemical properties and enhanced anti-bacterial activities. As such, AgNPs may provide newer strategies for treatment and prevention of dental infections. However, numerous concerns around the chemical synthesis of nanomaterials, which are not limited to cost and use of toxic reducing agents, have been raised. This has inspired the green synthesis route, which uses natural products as reducing agents. The biogenic AgNPs were reported to be biocompatible and environmentally friendly when compared to the chemically-synthesized AgNPs. As such, plant-synthesized AgNPs can be used as antimicrobial, antifouling, and remineralizing agents for management and treatment of dental infections and diseases.
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spelling pubmed-88756512022-02-26 Plant Extract-Synthesized Silver Nanoparticles for Application in Dental Therapy Ahmed, Omnia Sibuyi, Nicole Remaliah Samantha Fadaka, Adewale Oluwaseun Madiehe, Madimabe Abram Maboza, Ernest Meyer, Mervin Geerts, Greta Pharmaceutics Review Oral diseases are the most common non-communicable diseases in the world, with dental caries and periodontitis causing major health and social problems. These diseases can progress to systematic diseases and cause disfigurement when left untreated. However, treatment of oral diseases is among the most expensive treatments and often focus on restoration of form and function. Caries prevention has traditionally relied on oral hygiene and diet control, among other preventive measures. In this paper, these measures are not disqualified but are brought into a new context through the use of nanotechnology-based materials to improve these conventional therapeutic and preventive measures. Among inorganic nanomaterials, silver nanoparticles (AgNPs) have shown promising outcomes in dental therapy, due to their unique physicochemical properties and enhanced anti-bacterial activities. As such, AgNPs may provide newer strategies for treatment and prevention of dental infections. However, numerous concerns around the chemical synthesis of nanomaterials, which are not limited to cost and use of toxic reducing agents, have been raised. This has inspired the green synthesis route, which uses natural products as reducing agents. The biogenic AgNPs were reported to be biocompatible and environmentally friendly when compared to the chemically-synthesized AgNPs. As such, plant-synthesized AgNPs can be used as antimicrobial, antifouling, and remineralizing agents for management and treatment of dental infections and diseases. MDPI 2022-02-08 /pmc/articles/PMC8875651/ /pubmed/35214112 http://dx.doi.org/10.3390/pharmaceutics14020380 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Ahmed, Omnia
Sibuyi, Nicole Remaliah Samantha
Fadaka, Adewale Oluwaseun
Madiehe, Madimabe Abram
Maboza, Ernest
Meyer, Mervin
Geerts, Greta
Plant Extract-Synthesized Silver Nanoparticles for Application in Dental Therapy
title Plant Extract-Synthesized Silver Nanoparticles for Application in Dental Therapy
title_full Plant Extract-Synthesized Silver Nanoparticles for Application in Dental Therapy
title_fullStr Plant Extract-Synthesized Silver Nanoparticles for Application in Dental Therapy
title_full_unstemmed Plant Extract-Synthesized Silver Nanoparticles for Application in Dental Therapy
title_short Plant Extract-Synthesized Silver Nanoparticles for Application in Dental Therapy
title_sort plant extract-synthesized silver nanoparticles for application in dental therapy
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875651/
https://www.ncbi.nlm.nih.gov/pubmed/35214112
http://dx.doi.org/10.3390/pharmaceutics14020380
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