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Synthesis, Characterization and Host-Guest Complexation of Asplatin: Improved In Vitro Cytotoxicity and Biocompatibility as Compared to Cisplatin

Para-sulfocalix[n]arenes are promising host molecules that can accommodate various chemotherapeutic drugs. Pt(IV)-based complexes, including satraplatin and asplatin, are promising alternatives that overcome the shortcomings of Pt(II) complexes. In this study, asplatin has been synthesized by fusing...

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Detalles Bibliográficos
Autores principales: Fahmy, Sherif Ashraf, Ponte, Fortuna, Grande, Giulia, Fawzy, Iten M., Mandour, Asmaa A., Sicilia, Emilia, Azzazy, Hassan Mohamed El-Said
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875750/
https://www.ncbi.nlm.nih.gov/pubmed/35215372
http://dx.doi.org/10.3390/ph15020259