Structure Based Affinity Maturation and Characterizing of SARS-CoV Antibody CR3022 against SARS-CoV-2 by Computational and Experimental Approaches

The COVID-19 epidemic is raging around the world. Neutralizing antibodies are powerful tools for the prevention and treatment of SARS-CoV-2 infection. Antibody CR3022, a SARS-CoV neutralizing antibody, was found to cross-react with SARS-CoV-2, but its affinity was lower than that of its binding with...

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Detalles Bibliográficos
Autores principales: Yu, Wei, Zhong, Nan, Li, Xin, Ren, Jiayi, Wang, Yueming, Li, Chengming, Yao, Gui, Zhu, Rui, Wang, Xiaoli, Jia, Zhenxing, Wu, Changwen, Chen, Rongfeng, Zheng, Weihong, Liao, Huaxin, Wu, Xiaomin, Yuan, Xiaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875849/
https://www.ncbi.nlm.nih.gov/pubmed/35215781
http://dx.doi.org/10.3390/v14020186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875849/
https://www.ncbi.nlm.nih.gov/pubmed/35215781
http://dx.doi.org/10.3390/v14020186

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