Cargando…

Structure Based Affinity Maturation and Characterizing of SARS-CoV Antibody CR3022 against SARS-CoV-2 by Computational and Experimental Approaches

The COVID-19 epidemic is raging around the world. Neutralizing antibodies are powerful tools for the prevention and treatment of SARS-CoV-2 infection. Antibody CR3022, a SARS-CoV neutralizing antibody, was found to cross-react with SARS-CoV-2, but its affinity was lower than that of its binding with...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Wei, Zhong, Nan, Li, Xin, Ren, Jiayi, Wang, Yueming, Li, Chengming, Yao, Gui, Zhu, Rui, Wang, Xiaoli, Jia, Zhenxing, Wu, Changwen, Chen, Rongfeng, Zheng, Weihong, Liao, Huaxin, Wu, Xiaomin, Yuan, Xiaohui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875849/ https://www.ncbi.nlm.nih.gov/pubmed/35215781 http://dx.doi.org/10.3390/v14020186

Ejemplares similares

Computational Simulation of HIV Protease Inhibitors to the Main Protease (Mpro) of SARS-CoV-2: Implications for COVID-19 Drugs Design
por: Yu, Wei, et al.
Publicado: (2021)

Electrostatic Interactions Explain the Higher Binding Affinity of the CR3022 Antibody for SARS-CoV-2 than the 4A8 Antibody
por: Nguyen, Hung, et al.
Publicado: (2021)

Dissecting strategies to tune the therapeutic potential of SARS-CoV-2–specific monoclonal antibody CR3022
por: Atyeo, Caroline, et al.
Publicado: (2021)

Insights on the interaction of SARS-CoV-2 variant B.1.617.2 with antibody CR3022 and analysis of antibody resistance
por: KS, Sandhya, et al.
Publicado: (2023)

A neutralizing bispecific single-chain antibody against SARS-CoV-2 Omicron variant produced based on CR3022
por: Yu, Kaikai, et al.
Publicado: (2023)

Rapid production of SARS-CoV-2 receptor binding domain (RBD) and spike specific monoclonal antibody CR3022 in Nicotiana benthamiana
por: Rattanapisit, Kaewta, et al.
Publicado: (2020)

Corrigendum: A neutralizing bispecific single-chain antibody against SARS-CoV-2 Omicron variant produced based on CR3022
por: Yu, Kaikai, et al.
Publicado: (2023)

Production of scFv, Fab, and IgG of CR3022 Antibodies Against SARS-CoV-2 Using Silkworm-Baculovirus Expression System
por: Ebihara, Takeru, et al.
Publicado: (2021)

Development of a Single-Chain Variable Fragment of CR3022 for a Plasmonic-Based Biosensor Targeting the SARS-CoV-2 Spike Protein
por: Tohari, Taufik Ramdani, et al.
Publicado: (2022)

Comparative highlights on MERS-CoV, SARS-CoV-1, SARS-CoV-2, and NEO-CoV
por: Goyal, Rajat, et al.
Publicado: (2022)

A New Crystal Form of the SARS-CoV-2 Receptor Binding Domain: CR3022 Complex—An Ideal Target for In-Crystal Fragment Screening of the ACE2 Binding Site Surface
por: Nichols, Charlie, et al.
Publicado: (2020)

Binding affinity and mechanisms of SARS-CoV-2 variants
por: Han, Yanqiang, et al.
Publicado: (2021)

Human Coronaviruses SARS-CoV, MERS-CoV, and SARS-CoV-2 in Children
por: Aleebrahim-Dehkordi, Elahe, et al.
Publicado: (2021)

Data mining of coronavirus: SARS-CoV-2, SARS-CoV and MERS-CoV
por: Huh, Jung Eun, et al.
Publicado: (2021)

SARS-CoV, MERS-CoV and SARS-CoV-2: A Diagnostic Challenge
por: Ezhilan, Madeshwari, et al.
Publicado: (2021)

A Review of SARS-CoV2: Compared With SARS-CoV and MERS-CoV
por: Zhou, Huan, et al.
Publicado: (2021)

Transmission Cycle of SARS-CoV and SARS-CoV-2
por: Yadav, Tushar, et al.
Publicado: (2020)

Computational Saturation Mutagenesis of SARS-CoV-1 Spike Glycoprotein: Stability, Binding Affinity, and Comparison With SARS-CoV-2
por: Sobitan, Adebiyi, et al.
Publicado: (2021)

Mechanistic Origin of Different Binding Affinities of SARS-CoV and SARS-CoV-2 Spike RBDs to Human ACE2
por: Zhang, Zhi-Bi, et al.
Publicado: (2022)

Immune environment modulation in pneumonia patients caused by coronavirus: SARS-CoV, MERS-CoV and SARS-CoV-2
por: Yao, Zhixian, et al.
Publicado: (2020)

SARS-CoV, MERS-CoV and SARS-CoV-2 infections in pregnancy and fetal development
por: de Souza Silva, Guilherme Antonio, et al.
Publicado: (2020)

SARS-CoV-2, the other face to SARS-CoV and MERS-CoV: Future predictions
por: Abdelghany, T.M., et al.
Publicado: (2021)

Imaging findings in coronavirus infections: SARS-CoV, MERS-CoV, and SARS-CoV-2
por: Franquet, Tomas, et al.
Publicado: (2020)

Drug repurposing against SARS-CoV-1, SARS-CoV-2 and MERS-CoV
por: Aherfi, Sarah, et al.
Publicado: (2021)

Comparative susceptibility of SARS-CoV-2, SARS-CoV, and MERS-CoV across mammals
por: Li, Meng, et al.
Publicado: (2023)

Comparing SARS-CoV-2 with SARS-CoV and influenza pandemics
por: Petersen, Eskild, et al.
Publicado: (2020)

Correction to: Transmission Cycle of SARS-CoV and SARS-CoV-2
por: Yadav, Tushar, et al.
Publicado: (2020)

Comparing SARS-CoV-2 with SARS-CoV and influenza pandemics
por: Standl, Fabian, et al.
Publicado: (2021)

Amyloidogenic proteins in the SARS-CoV and SARS-CoV-2 proteomes
por: Bhardwaj, Taniya, et al.
Publicado: (2023)

Computational analysis of SARS-CoV-2, SARS-CoV, and MERS-CoV genome using MEGA
por: Sohpal, Vipan Kumar
Publicado: (2020)

The Comparative Immunological Characteristics of SARS-CoV, MERS-CoV, and SARS-CoV-2 Coronavirus Infections
por: Zhang, Yun-yu, et al.
Publicado: (2020)

Comparison of the COVID-2019 (SARS-CoV-2) pathogenesis with SARS-CoV and MERS-CoV infections
por: Fani, Mona, et al.
Publicado: (2020)

The emerging SARS-CoV, MERS-CoV, and SARS-CoV-2: An insight into the viruses zoonotic aspects
por: Al-Salihi, Karima A., et al.
Publicado: (2021)

SARS-Coronavirus (SARS-CoV)
por: Kehm, Roland
Publicado: (2009)

Structural Basis of SARS-CoV-2 and SARS-CoV Antibody Interactions
por: Gavor, Edem, et al.
Publicado: (2020)

Coronavirus in Continuous Flux: From SARS‐CoV to SARS‐CoV‐2
por: Dong, Yetian, et al.
Publicado: (2020)

Differential Tropism of SARS-CoV and SARS-CoV-2 in Bat Cells
por: Lau, Susanna K.P., et al.
Publicado: (2020)

Structure and Function of Major SARS-CoV-2 and SARS-CoV Proteins
por: Gorkhali, Ritesh, et al.
Publicado: (2021)

Electrostatic features for nucleocapsid proteins of SARS-CoV and SARS-CoV-2
por: Guo, Wenhan, et al.
Publicado: (2021)

A Comprehensive Review of Animal Models for Coronaviruses: SARS-CoV-2, SARS-CoV, and MERS-CoV
por: Singh, Ashutosh, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_5fkdorg4s0rjh43h15dj1qen2f