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Aetiological Characteristics of Infectious Diarrhea in Yantai City, Shandong Province, China in 2017

This study aimed to analyse the pathogenic spectrum and epidemiological characteristics of infectious diarrhea in Yantai City, Shandong Province, China and provide a reference for its prevention and control. A total of 713 stool specimens collected within 3 days of diarrhea onset from January to Dec...

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Autores principales: Sun, Zhenlu, Xu, Jinjie, Niu, Peihua, Jin, Miao, Gao, Qiao, Zhang, Ruiqing, Wang, Ji, Zhang, Yong, Ma, Xuejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875874/
https://www.ncbi.nlm.nih.gov/pubmed/35215810
http://dx.doi.org/10.3390/v14020216
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author Sun, Zhenlu
Xu, Jinjie
Niu, Peihua
Jin, Miao
Gao, Qiao
Zhang, Ruiqing
Wang, Ji
Zhang, Yong
Ma, Xuejun
author_facet Sun, Zhenlu
Xu, Jinjie
Niu, Peihua
Jin, Miao
Gao, Qiao
Zhang, Ruiqing
Wang, Ji
Zhang, Yong
Ma, Xuejun
author_sort Sun, Zhenlu
collection PubMed
description This study aimed to analyse the pathogenic spectrum and epidemiological characteristics of infectious diarrhea in Yantai City, Shandong Province, China and provide a reference for its prevention and control. A total of 713 stool specimens collected within 3 days of diarrhea onset from January to December 2017 at secondary or higher hospitals in Yantai City were tested for 10 causative pathogens, using real-time polymerase chain reaction (RT-PCR). The top two rotaviruses and norovirus were analysed for typing and geographical distribution. The total positive rate was 46.56% (332/713), and 268 of 713 specimens contained at least one pathogen; 64 had at least two pathogens, accounting for 19.28% of the positive specimens (64/332). The positivity rates of rotavirus (RV), norovirus (NoVs) GI, norovirus (NoVs) GII, enterovirus universal (EV), enteric adenoviruses (EAdV), sapovirus (SaV), astrovirus (Astv), Salmonella (SE), Listeria monocytogenes (LiMo), and Vibrio parahaemolyticus (VP) were 20.06% (143/713), 1.82% (13/713), 12.84% (89/713), 10.66% (76/713), 4.07% (29/713), 0.42% (3/713), 2.38% (17/713), 1.54% (11/713), 1.82% (13/713), and 1.54% (11/713), respectively. Infectious diarrhea showed a high prevalence in young children aged 1-5 years, accounting for 48.6% of the total number of cases. Bacterial diarrhea was predominant in summer, and viral diarrhea was distributed throughout the year, without a significant seasonal pattern. Rotavirus is dominated by G9P, accounting for 81.82%, while norovirus is dominated by the GII type and has diverse characteristics. The aetiology of infectious diarrhea in Yantai is mainly viral, with RV, NoVs, EV, EAdV, and Astv being the most frequent pathogens. Continuous surveillance of infectious diarrhea diseases can help us understand its epidemiological and pathogenic characteristics, thereby taking targeted preventive and control measures in different seasons.
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spelling pubmed-88758742022-02-26 Aetiological Characteristics of Infectious Diarrhea in Yantai City, Shandong Province, China in 2017 Sun, Zhenlu Xu, Jinjie Niu, Peihua Jin, Miao Gao, Qiao Zhang, Ruiqing Wang, Ji Zhang, Yong Ma, Xuejun Viruses Brief Report This study aimed to analyse the pathogenic spectrum and epidemiological characteristics of infectious diarrhea in Yantai City, Shandong Province, China and provide a reference for its prevention and control. A total of 713 stool specimens collected within 3 days of diarrhea onset from January to December 2017 at secondary or higher hospitals in Yantai City were tested for 10 causative pathogens, using real-time polymerase chain reaction (RT-PCR). The top two rotaviruses and norovirus were analysed for typing and geographical distribution. The total positive rate was 46.56% (332/713), and 268 of 713 specimens contained at least one pathogen; 64 had at least two pathogens, accounting for 19.28% of the positive specimens (64/332). The positivity rates of rotavirus (RV), norovirus (NoVs) GI, norovirus (NoVs) GII, enterovirus universal (EV), enteric adenoviruses (EAdV), sapovirus (SaV), astrovirus (Astv), Salmonella (SE), Listeria monocytogenes (LiMo), and Vibrio parahaemolyticus (VP) were 20.06% (143/713), 1.82% (13/713), 12.84% (89/713), 10.66% (76/713), 4.07% (29/713), 0.42% (3/713), 2.38% (17/713), 1.54% (11/713), 1.82% (13/713), and 1.54% (11/713), respectively. Infectious diarrhea showed a high prevalence in young children aged 1-5 years, accounting for 48.6% of the total number of cases. Bacterial diarrhea was predominant in summer, and viral diarrhea was distributed throughout the year, without a significant seasonal pattern. Rotavirus is dominated by G9P, accounting for 81.82%, while norovirus is dominated by the GII type and has diverse characteristics. The aetiology of infectious diarrhea in Yantai is mainly viral, with RV, NoVs, EV, EAdV, and Astv being the most frequent pathogens. Continuous surveillance of infectious diarrhea diseases can help us understand its epidemiological and pathogenic characteristics, thereby taking targeted preventive and control measures in different seasons. MDPI 2022-01-23 /pmc/articles/PMC8875874/ /pubmed/35215810 http://dx.doi.org/10.3390/v14020216 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Brief Report
Sun, Zhenlu
Xu, Jinjie
Niu, Peihua
Jin, Miao
Gao, Qiao
Zhang, Ruiqing
Wang, Ji
Zhang, Yong
Ma, Xuejun
Aetiological Characteristics of Infectious Diarrhea in Yantai City, Shandong Province, China in 2017
title Aetiological Characteristics of Infectious Diarrhea in Yantai City, Shandong Province, China in 2017
title_full Aetiological Characteristics of Infectious Diarrhea in Yantai City, Shandong Province, China in 2017
title_fullStr Aetiological Characteristics of Infectious Diarrhea in Yantai City, Shandong Province, China in 2017
title_full_unstemmed Aetiological Characteristics of Infectious Diarrhea in Yantai City, Shandong Province, China in 2017
title_short Aetiological Characteristics of Infectious Diarrhea in Yantai City, Shandong Province, China in 2017
title_sort aetiological characteristics of infectious diarrhea in yantai city, shandong province, china in 2017
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875874/
https://www.ncbi.nlm.nih.gov/pubmed/35215810
http://dx.doi.org/10.3390/v14020216
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