Dabigatran Acylglucuronide, the Major Metabolite of Dabigatran, Shows a Weaker Anticoagulant Effect than Dabigatran

Dabigatran (DAB) is an orally administered thrombin inhibitor. Both DAB and its main metabolite dabigatran acylglucuronide (DABG) have established anticoagulant effects. Here, we aimed to compare the relative anticoagulant effects of DABG and DAB in humans. Anticoagulant effects of DAB and DABG were...

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Autores principales: Kim, Jong-Min, Noh, Jihyeon, Park, Jin-Woo, Chung, Hyewon, Kim, Kyoung-Ah, Park, Seung Bin, Lee, Jun-Seok, Park, Ji-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875894/
https://www.ncbi.nlm.nih.gov/pubmed/35213990
http://dx.doi.org/10.3390/pharmaceutics14020257

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